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Basic and Clinical Neuroscience، جلد ۱۲، شماره ۱، صفحات ۸۹-۹۴
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عنوان انگلیسی The Factors Associated With Olfactory Dysfunction in Patients with Multiple Sclerosis
چکیده انگلیسی مقاله Introduction: An impaired sense of smell has a remarkable impact on the quality of life. It is seen in a variety of neurodegenerative diseases such as Parkinson disease. In this study, we assessed the olfactory function in patients with Multiple Sclerosis (MS) by Sniff Magnitude Test (SMT).  Methods: A cross-sectional study was conducted on 48 patients with MS. A questionnaire, including demographic and clinical variables, was completed for each patient. The SMT was used for the evaluation of olfactory function.  Results: Olfactory dysfunction was found in 14.6% of patients (8.3% hyposmia and 6.3% anosmia). Older age, longer disease duration, higher hospital admission rate, lower mini-mental status examination score, and secondary progressive course of MS were significantly related to olfactory dysfunction.  Conclusion: Secondary progressive MS and markers of advanced disease toward neurodegenerative phase (including older age, longer disease duration, and lower cognitive function) can be associated with olfactory dysfunction in MS patients.
کلیدواژه‌های انگلیسی مقاله Smell, Olfaction disorders, Anosmia, Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
نویسندگان مقاله | Mostafa Almasi
Department of Neurology, Firouzgar Hospital, Iran University of Medical Sciences, Tehran, Iran.


| Mohammad Ali Sahraian
Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.


| Fahimeh Haji Akhoundi
Department of Neurology, Firouzgar Hospital, Iran University of Medical Sciences, Tehran, Iran.


| Hamid Reza Ezzati
Department of Neurology, Hazrat Rasool Hospital, Iran University of Medical Sciences, Tehran, Iran.


| Mohammad Rohani
Department of Neurology, Hazrat Rasool Hospital, Iran University of Medical Sciences, Tehran, Iran.
نشانی اینترنتی http://bcn.iums.ac.ir/browse.php?a_code=A-10-1368-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Clinical Neuroscience
نوع مقاله منتشر شده Original
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