این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Basic and Clinical Neuroscience، جلد ۱۱، شماره ۵، صفحات ۶۱۹-۶۳۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Diagnostic Challenges and Prospects Associated With Zoonotic Tuberculosis of Central Nervous System
چکیده انگلیسی مقاله Introduction: The diagnosis of Tuberculous Meningitis (TBM) has remained a challenge due to its insidious onset and the failure of conventional diagnostic tests. The present study aimed to identify the mycobacterial pathogen in the CSF of patients with TBM and a poor prognosis. Methods: We retrospectively recruited 224 TBM and 34 non-TBM patients admitted to the Central India Institute of Medical Sciences, Nagpur, India, in 2014. The CSF samples of these patients were subjected to a duplex PCR assay for the species-specific identification of the causative pathogen. Results: M. bovis and infection with M.tuberculosis were detected in 7% (18) and 32.9% (85) of the patients, respectively. Moreover, 14% (36) of the study samples were culture positive; however, the mycobacterial pathogens could not be differentiated to the species level.  Conclusion: The present study findings emphasized the potentially vital importance of M. bovis identification for appropriate patient management. The obtained data also demonstrated the persistent significance of M. bovis, as a zoonotic pathogen.
کلیدواژه‌های انگلیسی مقاله Duplex PCR, Mycobacterium Bovis, Tuberculous meningitis, Zoonoses
نویسندگان مقاله | Prachi R. Bapat
Research Centre, Central India Institute of Medical Sciences, Nagpur, Maharashtra, India.


| Seema D. Shekhawat
Research Centre, Central India Institute of Medical Sciences, Nagpur, Maharashtra, India.


| Aliabbas A. Husain
Research Centre, Central India Institute of Medical Sciences, Nagpur, Maharashtra, India.


| Renuka S. Dodkey
Research Centre, Central India Institute of Medical Sciences, Nagpur, Maharashtra, India.


| Hatim F. Daginawala
Research Centre, Central India Institute of Medical Sciences, Nagpur, Maharashtra, India.


| Lokendra K. Singh
Research Centre, Central India Institute of Medical Sciences, Nagpur, Maharashtra, India.


| Rajpal S. Kashyap
Research Centre, Central India Institute of Medical Sciences, Nagpur, Maharashtra, India.
نشانی اینترنتی http://bcn.iums.ac.ir/browse.php?a_code=A-10-803-3&slc_lang=en&sid=1
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Clinical Neuroscience
نوع مقاله منتشر شده Original
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات