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Journal of Medical Signals and Sensors، جلد ۱۱، شماره ۱، صفحات ۴۵-۵۱
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عنوان انگلیسی Investigating the Dosimetric Characteristics of Microbeam Radiation Treatment
چکیده انگلیسی مقاله Background: High-radiation therapeutic gain could be achieved by the modern technique of microbeam radiation treatment (MRT). The aim of this study was to investigate the dosimetric properties of MRT. Methods: The EGSnrc Monte Carlo (MC) code system was used to transport photons and electrons in MRT. The mono-energetic beams (1 cm × 1 cm array) of 50, 100, and 150 keV and the spectrum photon beam (European Synchrotron Radiation Facility [ESRF]) were modeled to transport through multislit collimators with the aperture's widths of 25 and 50 and the center-to-center (c-t-c) distance between two adjacent microbeams (MBs) of 200 . The calculated phase spaces at the upper surface of water phantom (1 cm × 1 cm) were implemented in DOSXYZnrc code to calculate the percentage depth dose (PDD), the dose profile curves (in depths of 0-1, 1-2, and 3-4 cm), and the peak-to-valley dose ratios (PVDRs). Results: The PDD, dose profile curves, and PVDRs were calculated for different effective parameters. The more flatness of lateral dose profile was obtained for the ESRF spectrum MB. With constant c-t-c distance, an increase in the MB size increased the peak and valley dose; simultaneously, the PVDR was larger for the 25 MB (33.5) compared to 50 MB (21.9) beam, due to the decreased scattering photons followed to the lower overlapping of the adjacent MBs. An increase in the depth decreased the PVDRs (i.e., 54.9 in depth of 0-1 cm). Conclusion: Our MC model of MRT successfully calculated the effect of dosimetric parameters including photon's energy, beam width, and depth to estimate the dose distribution.
کلیدواژه‌های انگلیسی مقاله Dosimetry, microbeam radiation treatment, Monte Carlo simulation
نویسندگان مقاله | Mansour Zabihzadeh
Department of Medical Physics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences,


| Atefeh Rabiei
Department of Clinical Oncology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran


| Hojattollah Shahbazian
Department of Clinical Oncology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran


| Sasan Razmjoo


نشانی اینترنتی http://jmss.mui.ac.ir/index.php/jmss/article/view/565
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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