این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Neonatology، جلد ۱۲، شماره ۴، صفحات ۳۰-۳۹
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Early-Onset Neonatal Sepsis: A Retrospective Study among 1,119 Moroccan Newborns Admitted to the National Reference Center in Neonatology and Nutrition, Rabat, Morocco
چکیده انگلیسی مقاله Background: Early-onset neonatal sepsis is recognized as a common and serious problem for neonates. The clinical manifestations of neonatal sepsis are nonspecific and have varied clinical features. Therefore, their diagnosis is based on a combination of clinical presentation, the use of biological tests, and anamnestic arguments. The present study aimed to describe the infection risk factors, as well as clinical, paraclinical, and evolutionary characteristics of newborns with suspected early-onset neonatal sepsis and highlight the importance of C-reactive protein(CRP) to diagnose neonatal sepsis. Methods: This retrospective analytical study was conducted at the National Reference Center for Neonatology and Nutrition at Children's Hospital, University Hospital Centre IbnSina of Rabat, from January 1 to December 31, 2016. Results: During the study period, 1,199 newborns met the inclusion criteria. Upon admission, 52% of cases were under the age of one day. Symptomatic newborns represented 67.4% of the cases. The hospitalized cases with one or more infection risk factors were represented 80.3% of cases. The CRP was positive (> 20 mg/L) in 698 (58%) newborns. Univariate analysis pointed out that CRP value was significantly associated with age groups (P< 0.001), presence of at least one infectious risk factor (P< 0.001), as well as the presence of respiratory (P< 0.001), cutaneous (P< 0.001), circulatory (P=0.02), and neurological (P=0.008) symptoms. The diagnosis of early-onset neonatal infection with a meningeal, pulmonary, or ocular location was retained in 5%, 2%, and 0.2% of cases, respectively. The mortality rate was reported as 7%. Conclusion: Screening, management, and reduction of early-onset neonatal infection remain a crucial challenge, requiring coordination between pediatricians and obstetricians to obtain reliable data and identify newborns at risk.
کلیدواژه‌های انگلیسی مقاله C-reactive protein (CRP), Neonatal sepsis, Newborn, Risk factors 
نویسندگان مقاله | Kenza Hattoufi
National Reference Center in Neonatology and Nutrition, Children’s Hospital, University Hospital Centre IBN SINA, Rabat, Morocco. Research Team on Health and Nutrition of Mother and Child, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco


| Majdouline Obtel
Department of Public Health, Laboratory of Biostatistics, Clinical Research and Epidemiology, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco


| Hassan Aguenaou
Joint Research Unit in Nutrition and Food, RDC-Nutrition AFRA/IAEA, Ibn Tofail University-CNESTEN, Rabat-Kenitra, Morocco


| Aicha Kharbach
Research Team on Health and Nutrition of Mother and Child, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoResearch Team on Health and Nutrition of Mother and Child, Faculty of Medicine and Pharmacy, Mohammed V University. Gynaecology-Obstetrics and Endocrinology Department, Maternity Souissi, University Hospital Center IBN SINA, Rabat, Morocco


| Amina Barkat
National Reference Center in Neonatology and Nutrition, Children’s Hospital, University Hospital Centre IBN SINA, Rabat, MoroccoResearch Team on Health and Nutrition of Mother and Child, Faculty of Medicine and Pharmacy, Mohammed
نشانی اینترنتی https://ijn.mums.ac.ir/article_19044.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده تحقیقی اصیل
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات