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Avicenna Journal of Phytomedicine، جلد ۱۰، شماره ۵، صفحات ۵۲۳-۵۳۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Comparison between Golnar product and placebo in heavy menstrual bleeding: A double-blind randomized clinical trial
چکیده انگلیسی مقاله Objective: Golnar product is a poly herbal formulation advised by Persian medicine to control heavy menstrual bleeding (HMB). This study was conducted to compare the efficacy of this product with placebo in patients with HMB. Materials and Methods: In this double-blind randomized clinical trial, 100 women with HMB were randomly assigned into two groups. The patients in the Golnar group (n=50) took Golnar capsules 500 mg three times a day for the first 7 days of menstrual cycle for three cycles. The placebo group (n=50), took placebo capsules in the same manner. The duration and volume of bleeding (using Pictorial Blood Loss Assessment Chart: PBAC), quality of life (using Menorrhagia Questionnaire: MQ), and hemoglobin level (Hb) were measured 3 months after initiation of the intervention. Results: Eighty-two patients (43 in the Golnar and 39 in the placebo groups) completed the 3-month intervention period. In the Golnar group, PBAC score decreased from 201.62 (144.11) to 109.44 (69.57) (p< 0.001) and MQ score improved significantly from 0.58 (0.27) to 0.39 (0.31) (p< 0.001), while changes in placebo group were not significant. Hb increased in the Golnar group from 12.78±0.98 to 12.97±0.95 mg/dl (p=0.048) and decreased in the placebo group from 12.94±1.08 to 12.44±1.01mg/dl (p< 0.001). No significant adverse effects were found in the Golnar group. Conclusion: The Golnar product can be considered an effective intervention for patients with HMB. Assessment of side-effects is suggested to be performed in a larger sample. In addition, a comparison between the Golnar product and nonsteroidal anti-inflammatory drugs could be valuable.
کلیدواژه‌های انگلیسی مقاله Persian Medicine, Herbal Medicine, uterine hemorrhage, Menorrhagia, Clinical trial
نویسندگان مقاله | Fataneh Hashem-Dabaghian
1- Research Institute for Islamic and Complementary Medicine, School of Persian medicine, Iran University of Medical Sciences, Tehran, Iran. 2- School of Persian medicine, Iran University of Medical Sciences, Tehran, Iran


| Fatemeh Yousefi
1- Research Institute for Islamic and Complementary Medicine, School of Persian medicine, Iran University of Medical Sciences, Tehran, Iran. 2- School of Persian medicine, Iran University of Medical Sciences, Tehran, Iran


| Maryam Kashanian
Department of Obstetrics and Gynecology, Iran University of Medical Science, Tehran, Iran.


| Ismail Nazem
Department of Persian medicine, School of Persian medicine, Tehran University of medical Science, Tehran, Iran.


| sodabeh bioos
Department of Persian medicine, School of Persian medicine, Tehran University of medical Science, Tehran, Iran.


| Omod sadeghpour
1- Research Institute for Islamic and Complementary Medicine, School of Persian medicine, Iran University of Medical Sciences, Tehran, Iran. 2- School of Persian medicine, Iran University of Medical Sciences, Tehran, Iran


| Jaleh Aliasl
Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran
نشانی اینترنتی https://ajp.mums.ac.ir/article_15528.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Research Article
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