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World Journal of Plastic Surgery، جلد ۱۱، شماره ۱، صفحات ۱۳۱-۱۳۳
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عنوان انگلیسی A Rare Case of a Chemical Burn: Dithranol with Salicylic Acid
چکیده انگلیسی مقاله A 16-year-old female with psoriasis presented to our Plastic Surgery Department with a significant chemical burn to the neck, upper torso and left cheek (TBSA 6%). She applied a concoction of cream prescribed by her dermatologist in her native country, Poland when she returned to the United Kingdom. A few hours after application she developed a burn with pH of 5. A review of the cream revealed a mixture of 19% dithranol and 5% salicylic acid. This combination is recognized for managing psoriasis, however the strength of dithranol in the combination given is of a high concentration (normally < 3%). This alone can cause a burn to the skin if left for a prolonged period of time. Salicylic acid is an enhancer which augments the stability of dithranol and increases its penetration and efficacy. The concentration of 5% is also on the higher end. Our patient was admitted for pain relief and further irrigation till normalization of the pH which was achieved after 3 days.  A worrying aspect in our patients' case is that she was given the cream to commence at home. High concentration preparation is normally commenced in a controlled setting under medical supervision.
کلیدواژه‌های انگلیسی مقاله Dithranol, Salicylic Acid, Chemical Burn, Psoriasis
نویسندگان مقاله | Dharshanan Raj Selvaraj
Department of Plastic Surgery, Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom


| Bismark Adjei
Department of Plastic Surgery, Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom


| Omar Farooq AL-NAHHAS
Department of Plastic Surgery, Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom


| Lutfi Kamil
Department of Plastic Surgery, Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom


| Indira Yonjan
Department of Plastic Surgery, Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom
نشانی اینترنتی http://wjps.ir/browse.php?a_code=A-10-691-2&slc_lang=en&sid=1
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