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JCR 2016
جستجوی مقالات
یکشنبه 23 آذر 1404
World Journal of Plastic Surgery
، جلد ۱۰، شماره ۱، صفحات ۸۵-۹۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Effect of White Tea (Camellia sinensis) Extract on Skin Wound Healing Process in Rats
چکیده انگلیسی مقاله
BACKGROUND White tea (Camellia sinensis) has anti-inflammatory and antioxidant properties and a protective effect against wrinkles, sunburn and UV damages on the skin. Thus, we aimed to evaluate the effect of white tea extract on the healing process of skin wounds in rats. METHODS This study was done in the Research Center of Shahrekord University of Medical Sciences, Shahrekord, Iran in 2019. Excisional skin wounds were created on five groups of healthy male Wistar rats (200-250 g, n=21) including control group, Eucerin-treated group, white tea 5% ointment (Eucerin) treated group, gel-treated group, white tea 5% gel treated group. Treatment was begun on day 1 and repeated every day at the same time until day 15. Pathologic samples were taken on days 4, 7 and 15 for histopathological examinations. Kruskal-Wallis test was used to analyze data by SPSS. Statistical significance was defined as P< 0.05. RESULTS Wound closure rate of control group was more than other groups on day 4 (P< 0.05). On day 7, reepithelisation and granulation tissue of control group were more than white tea 5% ointment-treated and its inflammation was less than others (P< 0.05). Neo-vascularization of white tea 5% ointment-treated group was more than control group on days 4 and 15 (P< 0.05). On day 4, intact mast cells of control group were more than white tea treated groups (P< 0.05). Degranulated mast cells of white tea 5% gel treated group was significantly (P< 0.05) more than control group on days 4 and 15. CONCLUSION Five percent white tea extract could not help the skin wound healing process.
کلیدواژههای انگلیسی مقاله
Antioxidant, Camellia sinensis, Cutaneous wound, Healing process, White tea
نویسندگان مقاله
| Golnoush Kouhihabibidehkordi
Medical Plants Research Center, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
| Soleiman Kheiri
Department of Biostatistics and Epidemiology, Faculty of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran
| Iraj Karimi
Department of Pathology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran
| Fatemeh Taheri
Department of Pathology, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
| Elham Bijad
Medical Plants Research Center, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
| Mohammad Bahadoram
Medicinal Plant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
| Zahra Alibabaie
Medical Plants Research Center, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
| Shirin Asgharian
Medical Plants Research Center, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
| Hajar Zamani
Medical Plants Research Center, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
| Mahmoud Rafieian-Kopaei
Medical Plants Research Center, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
نشانی اینترنتی
http://wjps.ir/browse.php?a_code=A-10-466-14&slc_lang=en&sid=1
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