| چکیده انگلیسی مقاله |
Background & Aims of the Study: Since beta-thalassemia is the most commonly inherited disease in Iran, its preventive and controlling programs are considered vitally important in the healthcare system. This study was conducted to investigate the incidence rate and epidemiology of major beta-thalassemia (MBT) over the last twenty years in Kerman, Iran. Materials and Methods: This cross-sectional study, as a kind of health system research, carried was out on all patients with beta-thalassemia (born from March 1998 to March 2018) registered in Kerman Health Center. The data, extracted from the national records of genetic diseases, were analyzed in SPSS software (version 16) using Fisher's exact test. Results: Based on the results of the present study, the incidence rate of MBT was calculated at 0.99 cases per 10,000 live births. According to this result, 29 subjects with MBT were born from 1998 to 2018. The most important cause of thalassemia was determined as non-identification of thalassemia minor in carrier couples and their lack of awareness about their complication (62%). The other cause was the non-cooperation of screened carrier couples in attending prenatal diagnosis (20.7%). It was revealed that in 23 MBT cases, the parents were relatives (79.3%). The diagnosis of 62% of patients had been made before they turned one year. Conclusion: It is recommended that the following measures been adopted to avoid MBT incidence: strengthening the care team, cooperating with gynecologists in identifying pregnant women suspected of having thalassemia minor in the first weeks of pregnancy and referring them to genetic counseling centers for condition determination, educating families and changing carrier couples attitudes toward abortion, monitoring and improving screening laboratories, and implementing public education programs for specific groups. |
| نویسندگان مقاله |
عصمت رضابیگی داورانی | Esmat Rezabeigi Davarani
Health Services Management Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
فاطمه محسنی تکلو | Fatemeh Mohseni Takaloo
Deputy of Health, Kerman University of Medical Sciences, Kerman, Iran
Province Health Center, Kerman University of Medical Sciences, Kerman, Iran
آذر وحیدنیا | Azar Vahidnia
Health Services Management Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
سلمان دانشی | Salman Daneshi
Department of Public Health, School of Health, Jiroft University of Medical Sciences, Jiroft, Iran
Department of Public Health, School of Health, Jiroft University of Medical Sciences, Iran
مریم رضابیگی داورانی | Maryam Rezabeigi Davarani
Faculty of Psychology and Educational Sciences, Allameh Tabataba'i University, Tehran, Iran
Faculty of Psychology & Educational Sciences, Allameh Tabatabai University of Tehran, Iran
نرگس خانجانی | Narges Khanjani
epartment of Epidemiology and Biostatistics, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran
Department of Epidemiology and Biostatistics, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran
کیاوش هوشمندی | Kiavash Hushmandi
Department of Food Hygiene and Quality Control, Division of Epidemiology and Zoonoses, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Department of Food Hygiene and Quality Control, Division of Epidemiology & Zoonoses, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
مهدی راعی | Mehdi Raei
Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
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