این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Health Sciences، جلد ۹، شماره ۴، صفحات ۴۶-۵۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The Effects of Grape Seed Extract Supplementation on Exercise-Induced Oxidative Stress in Young Untrained Males
چکیده انگلیسی مقاله Background and purpose: The aim of this study was to determine the effect of acute aerobic exercise and 14-days grape seed extract supplementation on total antioxidant capacity, lipid peroxidation, and muscle cell damage biomarkers in untrained males. Materials and Methods: In a randomized, double-blinded, and placebo-controlled study, twenty-two male students (age 19±1 years, weight 67.44±7 kg, BMI 22±2, V̇O2max 39±2 ml/kg-1/min-1) were randomly assigned to two groups of grape seed extract and placebo (PLA) (GSE: 200 mg/day for two weeks). After subsequent 14-days of supplementation, subjects did a single session of aerobic exercise (running) on the treadmill at 75% VO2max for 30 minutes. Blood samples were taken 3 times: prior to supplementation (baseline), 14-days after supplementation, and immediately after exercise (post-exercise). Total antioxidant capacity (TAC), malondialdehyde (MDA), creatine kinase (CK), lactate dehydrogenase (LDH), and lactate were measured. TAC was determined by ABTs method. The collected data were then analyzed by running analysis of variance (ANOVA) with repeated measure and Bonferroni post-hoc tests as appropriate using SPSS17 at p< 0.05. Results: Malondialdehyde, CK, LDH, Lactate were significantly increased after aerobic exercise (p< 0.05). Short-term GSE supplementation significantly prevented MDA and CK cascade after exercise compared to PLA (p< 0.05) but, it had no significant effect on basal parameters (p>0.05). The exercise had also no significant effect on total antioxidant capacity in any of the groups (p>0.05). Conclusion: Aerobic exercise could increase blood oxidative stress biomarkers and GSE supplementation, due to the influential antioxidant effect; yet, it could attenuate exercise-induced oxidative stress in men.
کلیدواژه‌های انگلیسی مقاله Aerobic Exercise, Grape Seed Extract, Oxidative Stress, Antioxidant Effect, Supplementation
نویسندگان مقاله حمیدرضا زلفی | Hamidreza zolfi
Department of Physical Education and Sport Science, Technical and Vocational University (TVU), Tehran. Iran.
گروه تربیت بدنی و علوم ورزشی، دانشگاه فنی و حرفه ای، تهران، ایران

وحید ساری صراف | Vahid Sari-sarraf
Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Tabriz, Tabriz, Iran
گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران

حسین بابایی | Hossein Babaei
Drug Applied Research Center, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
مرکز تحقیقات کاربردی دارویی، دانشکده داروسازی، دانشگاه علوم پزشکی تبریز، تبریز، ایران

امیرمنصور وطن خواه | Amirmansour Vatankhah
MSc, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
مرکز تحقیقات کاربردی دارویی، دانشگاه علوم پزشکی تبریز، تبریز، ایران

نشانی اینترنتی http://jhs.mazums.ac.ir/browse.php?a_code=A-10-830-1&slc_lang=en&sid=1
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده بهداشت
نوع مقاله منتشر شده پژوهشی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات