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مجله حکیم سیداسماعیل جرجانی، جلد ۹، شماره ۱، صفحات ۱۶-۲۳
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عنوان انگلیسی The Effect of Training at Different Temperatures on The Gene Expression of GLUT4 and Insulin Receptor in the Brown Adipose Tissue of Streptozotocin-Induced Diabetic Rats
چکیده انگلیسی مقاله Background and Objective: Diabetes is one of the health problems in all societies. The aim of the present study was to investigate the effect of a period of training at different temperatures on the gene expression of GLUT_4 and insulin receptor in the brown adipose tissue of diabetic rats. Material and Methods: In this experimental study, 21 diabetic rats were randomly divided into 3 groups of 7 animals, including: (1) control (C), (2) swimming training at 5° C (S5ºC), and (3) swimming training at 36° C (S36ºC). Water swimming training was performed at 5±2° C and 36±2° C for six weeks, 5 sessions per week and 2-4 minutes per session. Data were analyzed using one-way analysis of variance and Tukey's post hoc test at the significance level of p≤0.05. Results: The gene expression of GLUT4 and insulin receptor in the S5º C and S36º C groups was significantly (P = 0.0001) higher than the control group. Also, the gene expression of GLUT4 in the S36º C group was higher than the S5º C group (p = 0.001), and the expression of insulin receptor in the S5º C group was significantly (p = 0.001) higher than the S36º C group. Conclusion: Swimming training at 5º C and 36º C significantly increased the gene expression of GLUT4 and insulin receptor in the brown adipose tissue of diabetic rats.
کلیدواژه‌های انگلیسی مقاله Physical Education and Training,GLUT4,Insulin Receptor,Diabetes
نویسندگان مقاله | Mojtaba Karimi Fard
Department of Physical Education and Sport Sciences, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran


| Ali Khajehlandi
Department of Physical Education and Sport Sciences, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
نشانی اینترنتی http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-724-4&slc_lang=en&sid=1
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