این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Medical Microbiology and Infectious Diseases، جلد ۸، شماره ۳، صفحات ۷۶-۸۳
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Prevalence and Risk Factors of Pulmonary Fungal Pathogens among Symptomatic Patients with or without Tuberculosis at Gombe, Nigeria
چکیده انگلیسی مقاله Introduction: Pulmonary fungal infections are a significant etiology of morbidity among immunocompromised and immunosuppressed patients. This study aimed to determine the prevalence of fungal pathogens and associated risk factors among pulmonary tuberculosis (PTB) and non-PTB patients attending Federal Teaching Hospital, Gombe, Nigeria. Methods: Three consecutive early morning sputum samples were collected from 43 PTB patients and 173 non-PTB persons and then examined for fungal pathogens using standard mycological stains, microscopy, and biochemical assays. All the participants were screened for HIV by the World Health Organization HIV testing algorithm and M. tuberculosis infection using GeneXpert ® nested PCR equipment. Samples with at least two significant fungal growths were considered positive. Results: Out of 216 sputa, 73.6% showed fungal growth in cultures. One hundred percent and 67% of PTB and non-PTB participants had positive sputa culture, respectively. In PTB patients, Candida albicans (25.6%) and Aspergillus fumigatus (20.9%), and in non-PTB individuals A. fumigatus (51.7%) and A. nigar (17.2%) were the most prevalent species. Age and residential areas were significantly associated with fungal infection in PTB and non-PTB subjects (p˂0.05). Cigarette smoking, prolonged antibiotic use, and having domestic pets were significant risk factors for developing pulmonary fungal infections in both groups (p˂0.05). None of the studied risk factors was significantly associated with pulmonary mycosis among TB patients (p˃0.05). However, prolonged use of antibiotics was a significant risk factor of pulmonary fungal infection among non-TB patients (p=0.009). Conclusion: Our study showed that PTB was a predisposing factor for fungal infection, especially among individuals with low socioeconomic status.
کلیدواژه‌های انگلیسی مقاله Pulmonary Symptoms, Risk factors, Fungal Infection, Mycosis, Tuberculosis coinfection
نویسندگان مقاله | Fatima Muhammad Sani
Department of Biological Sciences, Abubakar Tafawa Balewa University, Bauchi, Nigeria


| Idris Nasir Abdullahi
Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Ahmadu Bello University, Zaria, Nigeria


| Olawale Sunday Animasaun
Nigeria Field Epidemiology and Laboratory Training Program, African Field Epidemiology Network, Abuja, Nigeria


| Peter Elisha Ghamba
WHO National Polio Laboratory, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria


| Abubakar Umar Anka
Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Ahmadu Bello University, Zaria, Nigeria


| Matthew Oluwafemi Salami
Department of Medical Microbiology, Federal School of Medical Laboratory Science, Jos, Nigeria


| Amos Dangana
Department of Medical Laboratory Services, University of Abuja Teaching Hospital, Gwagwalada, Abuja Nigeria


| Dele Ohinoyi Amadu
Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Nigeria


| Ahaneku Iherue Osuji
Department of Medical Laboratory Services, University of Abuja Teaching Hospital, Gwagwalada, Abuja Nigeria
نشانی اینترنتی http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-38-2&slc_lang=en&sid=1
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious diseases and public health
نوع مقاله منتشر شده Original article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات