| چکیده انگلیسی مقاله |
Introduction/aims: Since the start of a pandemic from Wuhan, China in 2019, there is tremendous attention in the COVID-19 manifestation. One of the most important COVID-19 clinical presentations is gastrointestinal symptoms. The current systematic review study aims to focus on the implication of the gastrointestinal tract in patients infected with SARS-CoV-2.
Methods: For that we searched literature in MEDLINE, Scopus, Web of Science, and Embase. Also, the medRxiv was searched for preprints. The search was performed by using the following keywords "Covid-19", "Coronavirus", "SARS-CoV-2 infection", "SARS-CoV-2", "Gastrointestinal", "Gastrointestinal Tract", "digestive system". All the studies were conducted based on the PRISMA criteria.
Results: Of 3028 retrieved documents, 111 studies with 21126 COVID-19 cases were included. The prevalence of any Gastrointestinal symptoms was 17.22% (14.48 to 20.13). The prevalence of diarrhea was 13.75% (12.07 to 15.44), anorexia 27.41% (21.53 to 33.29) and Nausea/vomiting 8.11% (6.87 to 9.35). Furthermore, the prevalence of other symptoms in our current study was fever 76.70% (73.42 to 79.83), cough 58.07% (54.59 to 61.52) and dyspnea/shortness of breath 24.63% (20.06 to 29.48). According to meta-regression results, age (p: 0.027) and fever (p< 0.001) did have significant effect on prevalence of any Gastrointestinal symptoms.
Conclusion: The anorexia, diarrhea, nausea, and vomiting are the most common Gastrointestinal presentations. The majorities of studies are in the Case series setting and conducted in China. |
| نویسندگان مقاله |
| Saber Soltani
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
| Armin Zakeri
. Department of Hematology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
| Iraj Pakzad
Department of Microbiology, School of Allied Medical Sciences, Ilam University Medical Sciences, Ilam, Iran.
| Alireza Tabibzadeh
Department of VirologyDepartment of Virology, Iran University of Medical Sciences, Tehran, Iran., Iran University of Medical Sciences, Tehran, Iran.
| Amir Mohammad Zakeri
Pediatric Surgery Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Milad Zandi
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
| Sara Akhavan Rezayat
Department of Health Care Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
| Mehrzad Jafarzadeh
Endocrine research center, institute of Endocrinology and Metabolism, Iran University of Medical Science, Tehran, Iran.
| Parinaz Khalkhali Asl
Department of Microbiology, School of Medicine, Golestan University of Medical Sciences, Golestan, Iran.
| Arghavan Zebardast
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Yousef Erfani
Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Tehran University Medical Sciences, Tehran, Iran.
| Ramin Shahbahrami
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Reza Pakzad
Department of Epidemiology, Faculty of Health, Ilam University Medical Sciences, Ilam, Iran.
| Pooneh Malekifar
Department of Epidemiology, School of Public Health, Tehran University Medical Sciences, Tehran, Iran.
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