این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Archives of Anesthesiology and Critical Care، جلد ۶، شماره ۴، صفحات ۱۸۲-۱۸۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effect of Preoperative Dexmedetomidine on Prevalence of Postoperative Cognitive Dysfunction in Elderly Patients Candidate for Orthopedic Surgery under General Anesthesia
چکیده انگلیسی مقاله Background: Postoperative cognitive dysfunction (POCD) is amongst the most critical complications after surgery. This study shows the effect of dexmedetomidine on the prevalence of postoperative cognitive impairment. Methods: In this double-blinded clinical trial study, patients aged 60-80 years undergoing pelvic and femoral orthopedic surgery were randomly assigned in one of the two groups of the course, i.e., Dexmedetomidine (DEX) or normal saline (NS). We infuse One hour before anesthesia, one µg/kg dexmedetomidine in the group (DEX), and the same volume of normal saline (NS). Mini-Mental State Examination test (MMSE) was applied to evaluate the patients' cognitive condition, One day before the surgery, 24 and 72 hours after the surgery. Results: There was no significant difference between the two groups in terms of age, sex, duration of anesthesia, duration of surgery, and the amount of bleeding during operation (P>0.0). The postoperative hematocrit level was lower than the preoperative level in the group (DEX) (P< 0.05). There was no significant difference in MMSE test scores pre and postoperatively between the two groups (P>0.05). Conclusion: Dexmedetomidine infused before surgery has no preventive effect on POCD in elderly patients undergoing pelvic and femoral orthopedic surgery under general anesthesia.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Alireza Pournajafian
Department of Anesthesiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.


| Ali Khatibi
Department of Anesthesiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.


| Mohammad Reza Ghodraty
Department of Anesthesiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.


| Azadeh Emami
Department of Anesthesiology, Ali Asghar Hospital, Iran University of Medical Sciences, Tehran, Iran.


| Mona Haji Aghajani
School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
نشانی اینترنتی https://aacc.tums.ac.ir/index.php/aacc/article/view/305
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات