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Iranian Journal of Fisheries Sciences، جلد ۲۰، شماره ۳، صفحات ۷۴۱-۷۶۰
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عنوان انگلیسی Research Article: Histological study and evaluation of Hsp70 gene expression in gill and liver tissues of goldfish (Carassius auratus) exposed to Zinc oxide nanoparticles
چکیده انگلیسی مقاله In parallel with the increased use of nano-sized metallic materials, the possibility of their release into the environment has increased in recent decades. However, there is not sufficient information on the toxic potential of these materials on different aspects of the life history of aquatic organisms. In this study, we investigated the impact of zinc oxide nanoparticles (ZnO-NPs) on goldfish by studying histopathological alteration and Hsp70 gene expression in gill and liver tissues. The results showed that after exposure to different concentrations of ZnO-NPs, severe lesions were observed in the gill and liver tissues of goldfish. Expression of Hsp70 significantly increased in comparison with the control group and this increase was observed especially in the initial sampling times. Also expression pattern of Hsp70 is relatively similar in gill and liver tissues of goldfish. Based on the results of the present study, ZnO-NPs, as widely used nanoparticles can endanger the health of goldfish and further studies are needed to evaluate its potential toxic effects.
کلیدواژه‌های انگلیسی مقاله ZnO-NPs, Gene expression, Histopathology, Toxicity, Goldfish
نویسندگان مقاله | M. Harsij
Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran


| H. Paknejad
Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran


| M. Khalili
Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran.


| H. Jafarian
Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran


| S. Nazari
Cold-water Fishes Genetic and Breeding Research Center, Iranian Fisheries Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Yasouj, Iran
نشانی اینترنتی http://jifro.ir/browse.php?a_code=A-10-2717-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Genetics
نوع مقاله منتشر شده پژوهشی
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