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Journal of Reproduction and Infertility، جلد ۲۲، شماره ۳، صفحات ۲۱۶-۲۲۰
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عنوان انگلیسی Persistent Mullerian Duct Syndrome: A Rare Case of an Adult Infertile Male with Bilateral Cryptorchidism
چکیده انگلیسی مقاله Background: Persistent mullerian duct syndrome (PMDS) is a very rare form of internal male pseudohermaphroditism in individuals who are phenotypically males with 46 XY karyotypes harbouring internal female reproductive organs which are Mullerian derivatives. It occurs as a defect in the genes coding for the Mullerian inhibiting substance (MIS) or the anti Mullerian hormone (AMH) receptor, ultimately leading to failure of regression of Mullerian ducts. Case Presentation: A 29-year-old male with PMDS presented with complaints of primary infertility. Diagnosis was made with the help of high index of suspicion, radiological imaging, and karyotyping. Our patient underwent exploratory laparotomy with hysterectomy and bilateral orchidopexy. Conclusion: The purpose of this study was increasing awareness regarding rare entities and surgeons should have high clinical suspicion of PMDS when patient with bilateral undescended testis comes for the evaluation of primary infertility.
کلیدواژه‌های انگلیسی مقاله Anti Mullerian hormone (AMH), Cryptorchidism, Hysterectomy, Karyotyping, Mullerian inhibiting substance (MIS), Orchidopexy, Persistent mullerian duct syndrome (PMDS), Primary infertility
نویسندگان مقاله | Prakash Sankapal
Department of Urology, Grant Government Medical College and Sir JJ Hospital, Mumbai, India


| Venkat Gite
Department of Urology, Grant Government Medical College and Sir JJ Hospital, Mumbai, India


| Mayank Agrawal
Department of Urology, Grant Government Medical College and Sir JJ Hospital, Mumbai, India


| Mahesh Sane
Department of Urology, Grant Government Medical College and Sir JJ Hospital, Mumbai, India


| Atul Singal
Department of Urology, Grant Government Medical College and Sir JJ Hospital, Mumbai, India
نشانی اینترنتی https://www.jri.ir/article/120119
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