این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Reproduction and Infertility، جلد ۲۲، شماره ۲، صفحات ۱۰۳-۱۱۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluation of Microdissection Testicular Sperm Extraction (mTESE), Outcomes and Predictive Factors in Ireland: The Gold Standard for Men with Non-Obstructive Azoospermia
چکیده انگلیسی مقاله Background: Microdissection testicular sperm extraction (mTESE) is the gold standard approach in sperm retrieval in men with non-obstructive azoospermia (NOA). The purpose of the study was to assess the outcomes for Irish men who have undergone mTESE with a single surgeon. Methods: This is a retrospective, single cohort study. Thirty-four patients underwent mTESE between September 2015 and June 2019. A p< 0.05 was considered statistically significant. Results: In this study, sperm retrieval rate (SRR) was 47.06%. (16/34). The mean age in those who had retrieved sperm at mTESE was 37.9±2.6 years. Johnson Score (JS) and FSH were statistically different between successful and unsuccessful mTESE groups (p=0.017*10-5 and p=0.004, respectively). Optimal cutoff values for FSH, T and JS were 15 IU/L, 13 nmol/L and 5, respectively. The pregnancy rate was 63.64% (7/11) among men who went on to use mTESE sperm in an ICSI cycle. Conclusion: The combination of mTESE/Intracytoplasmic sperm injection (ICSI) is the best option available for men with NOA who prefer to achieve paternity using their own DNA. Given the overall SRRs in mTESE, it is imperative to continue research for a predictive model to better counsel azoospermic men regarding the use of mTESE. For this purpose, large, multicenter, randomized controlled trials are needed.
کلیدواژه‌های انگلیسی مقاله Male infertility, Microdissection testicular sperm extraction, Non-obstructive azoospermia, Predictive markers, Sperm retrieval
نویسندگان مقاله | Pat Rohan
Department of Urology, University Hospital Waterford, Waterford, Ireland


| Niamh Daly
Waterstone Clinic, Cork, Ireland


| Aoife O’Kelly
Department of Urology, University Hospital Waterford, Waterford, Ireland


| Martin O’Leary
College of Science, University College Dublin, Dublin, Ireland


| Tim Dineen
Waterstone Clinic, Cork, Ireland


| Nigam Shah
Department of Pathology, University Hospital Waterford, Waterford, Ireland


| Padraig Daly
Department of Urology, University Hospital Waterford, Waterford, Ireland


| John Waterstone
Waterstone Clinic, Cork, Ireland


| Ivor Cullen
Department of Urology, University Hospital Waterford, Waterford, Ireland
نشانی اینترنتی https://www.jri.ir/article/120107
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات