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Journal of Reproduction and Infertility، جلد ۲۳، شماره ۲، صفحات ۱۰۰-۱۰۷
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عنوان انگلیسی Comparison of Obstetric Outcomes Between IVF cycles with Donor Oocyte and Spontaneous Conception Pregnancies: A Retrospective Cohort study
چکیده انگلیسی مقاله Background: Oocyte donation has facilitated couples to achieve pregnancy in conditions like diminished ovarian reserve, premature ovarian failure, and inheritable disorders. However, it is unclear whether pregnancy complications are due to oocyte donation per se or due to confounding factors such as maternal age or the allogenic fetus. In this retrospective comparative cohort, an attempt was made to evaluate and compare multiple obstetric and perinatal outcomes. Methods: The present study comprised all women in the age range of 20-45 years who conceived from oocyte donation (n=102) between 1/12/2011 to 30/09/2017. Control group consisted of spontaneous conception cases (n=306) in ratio of 1:3 with no previous medical or surgery comorbidity. Obstetric and perinatal outcomes were compared between two groups. Results: Mean maternal age was significantly higher in the donor oocyte IVF group (group 1; 35.13 years) as compared to spontaneous conception group (group 2; 31.75 years). Parity between the two groups was comparable. Pregnancy induced hypertension (PIH) was seen in 33.33% of cases in group 1 as compared to 7.18% in group 2. Moreover, gestational diabetes mellitus was seen in 34.31% of cases in group 1 as compared to 9.47% in group 2 (p=0.001). By the same token, there was significant difference in perinatal outcomes between the two groups. Conclusion: Oocyte donation should be treated as an independent risk factor for miscarriage, hypertensive disorder, and gestational diabetes mellitus in pregnancy.
کلیدواژه‌های انگلیسی مقاله Bleeding in first trimester, Gestational diabetes mellitus, Oocyte donation, Pregnancy induced hypertension
نویسندگان مقاله | Yadav Vikas
Department of Obstetrics and Gynecology, School of Medical Sciences and Research, Sharda Hospital, Sharda University Campus, Uttar Pradesh, India


| Malhotra Neena
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India


| Mahey Reeta
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India


| Singh Neeta
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India


| Kriplani Alka
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
نشانی اینترنتی https://www.jri.ir/article/120141
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