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Journal of Biostatistics and Epidemiology، جلد ۸، شماره ۱، صفحات ۳۷-۴۴
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عنوان انگلیسی Prediction of the breast cancer mortality rate and its effective factors using genetic algorithm and logistic regression
چکیده انگلیسی مقاله Background: Logistic regression is one of the most common models used to predict and classify binary and multiple state responses in medicine. Genetic algorithms search techniques inspired by biology have recently been used successfully as a predictive model. Objective: The aim of this study was to use the genetic algorithm and logistic regression models in diagnosing and predicting factors affecting breast cancer mortality. Method: In this study, data of 2836 people with breast cancer during the years 2014-2018 was examined; their information was recorded in the cancer registration system of Kerman University of Medical Sciences. Death status was considered a dependent variable, while age, morphology, tumor differentiation (grad), residence status, and place of residence were considered independent variables. Sensitivity, specificity, accuracy, and area under the ROC curve were used to compare the models. Results: the logistic regression model determined factors affecting the breast cancer mortality rate, (with sensitivity (0.62), specificity (0.81), area under the ROC curve (0.74), and accuracy (0.84)), and genetic algorithm model (, with sensitivity (0.19), specificity (0.97), area under the ROC curve (0.58) and accuracy (0.87)). Conclusions: The sensitivity and area under the ROC curve of the logistic regression model were higher than those of the genetic algorithm, but the specificity and accuracy of the genetic algorithm were higher than those of the logistic regression. According to the purpose of the study, two models can be used simultaneously.
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نویسندگان مقاله | mahdieh mirzaie
Student of Biostatistics


| yunes jahani
Modeling in Health Research Center, Institute for Futures Studies in Health,Kerman University of Medical Sciences, Kerman,Iran 2-Department of Biostatistics and Epidemiology, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran


| abbas bahrampour
-Modeling in Health Research Center, Institute for Futures Studies in Health,Kerman University of Medical Sciences, Kerman,Iran 2-Department of Biostatistics and Epidemiology, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran
نشانی اینترنتی https://jbe.tums.ac.ir/index.php/jbe/article/view/650
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