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Iranian Journal of Microbiology، جلد ۱۴، شماره ۲، صفحات ۱۳۸-۱۴۴
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عنوان انگلیسی Seroprevalence of SARS-COV-2 antibodies among health-care workers exposed to COVID-19 patients in a large reference hospital, Iran
چکیده انگلیسی مقاله Background and Objectives: Health care workers (HCWs) are a high-risk group for acquiring and transmitting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Aim of the study was the evaluation of sero-prevalence of SARS-CoV-2 in a random sample of HCWs at a large acute care hospital in Iran. Materials and Methods: We collected blood samples of 180 medical staffs from September 22, 2020 to January 26, 2021. The enzyme linked immunosorbent assays (ELISA) tests were used for evaluation of the presence of IgG antibodies. Participants completed a self-report questionnaire, comprising demographics, occupational, the work area, and personal protection data. Results: Of the 180 HCWs who participated in this study, 44 (24.4%) were seropositive for anti-SARS-CoV-2 IgG. The percentage of IgG positivity was higher in males than females (P< 0.05). Also, there was statistically significant difference between presence of the antibodies and the occupation, location, and infecting family members with Covid -1 (P< 0.05). Other factors did not associate significantly to antibody presence against SARS-CoV-2 (P>0.05). Conclusion: According to this point that the number of COVID-19 cases is still growing rapidly among HCWs. So, the epidemiological estimate of SARS-CoV-2 infection remains a major challenge that is needed to prevent the spread of infection in the hospitals.
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نویسندگان مقاله | Abdol Sattar Pagheh
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran


| Arghavan Asghari
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran


| Khadijeh Abrari Romenjan
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran


| Tahoora Mousavi
Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran; Molecular and Cell Biology Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran


| Farshid Abedi
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran


| Arash Ziaee
Department of Neuroscience, Mashhad University of Medical Sciences, Mashhad, Iran


| Hakime Malakimoghadam
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran


| Masood Ziaee
Department of Neuroscience, Mashhad University of Medical Sciences, Mashhad, Iran
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/3319
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