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Iranian Journal of Medical Sciences، جلد ۴۷، شماره ۳، صفحات ۲۸۰-۲۸۴
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عنوان انگلیسی A Large Primary Retroperitoneal Synovial Sarcoma: A Case Report of a Huge Malignant Tumor
چکیده انگلیسی مقاله Synovial Sarcoma (SS) is a rare soft-tissue malignancy. Only about 15% of SS originates from the retroperitoneum. Retroperitoneal SS (RSS) is usually diagnosed incidentally due to the anatomy of the retroperitoneum. The most common complaints of patients are abdominal and low back pain. Other common symptoms of RSS are palpable abdominal mass, weight loss, and anemia. In this study, we will describe a 29-year-old white Asian man with a diagnosis of RSS after radical nephrectomy. He was admitted to the Urology Department of Shohada-e Tajrish hospital, Tehran, Iran in March 2019. The distinguishing feature of this case is the size of the mass, which has never been reported so much for retroperitoneal synovial sarcoma. Radiologic imaging showed a huge retroperitoneal mass originating from the kidney. Based on the pathologic features and immunohistochemistry (IHC) study, the diagnosis was consistent with synovial sarcoma. Accurate diagnosis of RSS is usually based on the pathological findings. Therefore, in case of doubt, a biopsy can be employed. Surgical resection of the tumor and lymph nodes dissection is the main and most important part of the treatment. Aggressive resection with free margin is recommended. The role of adjuvant and neoadjuvant chemotherapy in RSS is not certain to date, but it is recommended according to the patient’s condition.
کلیدواژه‌های انگلیسی مقاله Drug therapy, Retroperitoneal neoplasms, Synovial sarcoma
نویسندگان مقاله Anahita Ansari Djafari |
Department of Urology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Mohammadreza Razzaghi |
Department of Urology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Azadeh Rakhshan |
Department of Pathology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Saba Faraji |
Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran

Amir Hossein Rahavian |
Andrology Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Seyyed Ali Hojjati |
Department of Urology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

نشانی اینترنتی https://ijms.sums.ac.ir/article_47953_ef354f1741638bc1f3940c9951085897.pdf
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