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Journal of Research in Medical Sciences، جلد ۲۷، شماره ۲۲، صفحات ۲۰۲۲-۲۷
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عنوان انگلیسی Saffron (Crocus sativus L.) supplements improve quality of life and appetite in atherosclerosis patients: A randomized clinical trial
چکیده انگلیسی مقاله Background: Atherosclerosis is the most common cause of the ardiovascular disease. Saffron is a traditional food that affects many diseases and disorders. Therefore, the aim of this study was to identify the effects of Saffron (Crocus sativus L.) on quality of life (QOL) and appetite in patients with atherosclerosis. Materials and Methods: This was a randomized, double?blind, lacebo?controlled clinical trial. A total of 63 participants with therosclerosis were recruited from Emam Sajjad Hospital, Valiasr ospital, and Zafaranieyh Clinic in Tehran, Iran. The participants were divided randomly into two groups. Participants received 100 mg/d saffron or lacebo capsule for 6 weeks. QOL and appetite levels were measured by the McNew QOL questionnaire, and visual analog scale questionnaire, respectively. Furthermore, anthropometric indices of participants were measured before and after the intervention. Results: Statistical analysis showed that there was a statistically ignificant difference between atherosclerosis patients who received placebo and those who consumed saffron in terms of the physical omain (P = 0.008) and social domain (P = 0.012) of QOL. In the saffron group increased score in Total score Macnew (P < 0.001), physical omain (P = 0.025), and social domain (P < 0.001) was significant after the intervention. Moreover, the consumption of saffron did not ignificantly affect emotional domains of QOL, and appetite levels Conclusion: Saffron may be considered as a novel agent in patients with atherosclerosis to improve the QOL. A great deal of further research will be needed to critically validate the efficacy of saffron and its echanisms in atherosclerosis.
کلیدواژه‌های انگلیسی مقاله Appetite levels, atherosclerosis, cardiovascular disease, quality of life, saffron
نویسندگان مقاله | Shonaz Ahmadikhatir


| Alireza Ostadrahimi


| Abdolrasoul Safaiyan


| Shoyar Ahmadikhatir


| Nazila Farrin


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/11337
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نوع مقاله منتشر شده Original Article
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