این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Health Sciences and Surveillance System، جلد ۱۰، شماره ۲، صفحات ۱۵۰-۱۵۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Reference Range of Serum Zinc Concentration in Patients with Heart Failure: A Systematic Review and Meta-analysis of Cross-Sectional Studies in the 21st Century
چکیده انگلیسی مقاله Background: Heart failure (HF) is a clinical disorder and Zinc is an important cofactor in regulating oxidative status.The present study aimed to determine the mean concentration of serum zinc in patients with HF. Methods: PubMed, Embase, Scopus, and Web of Science were used in the present systematic review and meta-analysis to find relevant cross-sectional studies up to 1st January 2020. A random-effects model was used to pool the effect size (ES) and 95 % confidence intervals (CI). In addition, meta-regression analysis was performed to find the sources of statistical heterogeneity among the studies. Results: Our meta-analysis of 1358 HF patients indicated that their mean serum zinc concentration was 66.24 µg/dl (95 % CI: 59.16, 73.33). In sub-analysis, the mean concentration was 75.04 µg/dl and 52.90 µg/dl in patients < 65 years and > 65 years old, respectively. Subgroup analysis by geographical region showed that mean serum zinc was 70.70 µg/dl, 69.08 µg/dl and 60.91 µg/dl in HF patients from Europe, America, and Asia, respectively. Meta-regression analysis indicated a reduction of 1.42 µg/dl in serum zinc per each year of aging. Conclusion: In summary, our meta-analysis indicates that serum zinc concentrations have a narrow range in HF patients worldwide that declines with age and varies with geographical region. Additionally, serum zinc concentrations are lower in HF patients, specifically in the elderly.
کلیدواژه‌های انگلیسی مقاله Cardiovascular diseases, Heart Failure, Trace elements, zinc
نویسندگان مقاله Mohammad Jalali |
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran

Michael E Symonds |
The Early Life Research Unit, Academic Division of Child Health, Obstetrics and Gynaecology, and Nottingham Digestive Disease Centre and Biomedical Research Centre, The School of Medicine, The University of Nottingham, Nottingham, NG7 2UH, United Kingdom

Morteza Zare |
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

Zahra Sohrabi |
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

نشانی اینترنتی https://jhsss.sums.ac.ir/article_48288_9a48b15558d41b5b30825ba1f07cf51c.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات