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Middle East Journal of Cancer، جلد ۱۳، شماره ۲، صفحات ۲۹۳-۲۹۸
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عنوان انگلیسی The Investigation of Prophylactic Effect of StrataXRT Gel on Radiation-Induced Dermatitis in Breast Cancer Patients: A Randomized Clinical Trial
چکیده انگلیسی مقاله Background: Breast cancer is among the most prevalent cancers in women. Radiotherapy is an important part in treatment of breast cancer, associated with some side-effects, including skin dermatitis. Dermatitis may be severe and impair quality of life. Multiple agents have been studied, but no standard treatment is yet available. Silicone based gel (StrataXRT) was promising in some studies in reducing skin inflammation and also radiotherapy-induced dermatitis. Method: This was a randomized trial on 100 women with breast cancer who had undergone quadrantectomy for breast cancer. They received StrataXRT gel or best supportive care during radiotherapy. Dermatitis area and grade of dermatitis were measured. Results: Regarding the mean size of radiation-induced dermatitis area, there was a significant difference between the intervention (36.88 cm2 ± 69.93) and control (83.83 cm2 ± 79.34) groups (P = 0.002). During radiotherapy, except in the fourth week, dermatitis was significantly more severe in the control group. Conclusion: It seems that StrataXRT is helpful in decreasing radiotherapy-induced dermatitis.
کلیدواژه‌های انگلیسی مقاله Breast neoplasms, Radiotherapy, Dermatitis
نویسندگان مقاله Shapour Omidvari |
Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Zahra Eskandari |
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran

Hamid Nasrollahi |
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran

Niloofar Ahmadloo |
Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Mansour Ansari |
Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Seyed Hassan Hamedi |
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran

Nezhat Khanjani |
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran

Behnam Kadkhodaei |
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran

Ahmad Mosalaei |
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran

Mohammad Mohammadianpanah |
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

نشانی اینترنتی https://mejc.sums.ac.ir/article_47970_457bc72dda36f0c77ca20cf305f36bae.pdf
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