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International Journal of Organ Transplantation Medicine، جلد ۱۳، شماره ۱، صفحات ۰-۰
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عنوان انگلیسی Bone density reduction and related factors in renal transplant recipients: a cross-sectional study
چکیده انگلیسی مقاله Background: Decrease in Bone Mineral Density (BMD) is one of the complications of kidney transplantation in which many factors are involved. The results of studies are different and contradictory. Objective: to investigate the prevalence and related factors influencing BMD in renal transplant recipients. Methods: all kidney recipients (69 patients) referring to the Shahid Mostafa Khomeini Hospital, Ilam, Southwest of Iran, were included between 2016 and 2018. BMD of the lumbar spine and femoral neck was performed using dual-energy X-ray absorptiometry (DEXA). According to Z- score and T- score, patients were divided into two groups: fewer than 50 and over 50 age years. All demographic, background variables and laboratory parameters were evaluated. Descriptive statistics and Binary and multinomial logistic regression were used to analyze. Results: The overall prevalence of osteoporosis in the femur and lumbar spine was 38% and 32%, respectively. In patients under 50 years, Osteoporosis in the femur showed a significant relationship with vitamin D level and gender. In patients over 50 years, increased age and length of prednisolone consumption were associated with an increased risk of osteoporosis and osteopenia in the femoral neck (P < 0.05). Moreover, the length of use of prednisolone was associated with osteoporosis in the lumbar spine (RRR=1.02; p < 0.05). Conclusion: various factors such as prednisolone consumption affect BMD reduction in renal transplant recipients. Regular monitoring of BMD, reducing prednisolone dose as much as possible, training on effective supplements, and other preventive and supportive measures can be helpful and necessary.
کلیدواژه‌های انگلیسی مقاله Bone mineral density, Renal transplantation, Osteoporosis, Osteopenia, Prednisolone
نویسندگان مقاله | Bahareh Gheiasi
Assistant Professor of Nephrology, School of Medicine, Shahid Mostafa Khomaeini Hospital, Ilam University of Medical sciences. https://orcid.org/0000-0001-5467-8093


| Marzieh Hadavi
Assistant Professor of Endocrinology & Metabolism, Department of Internal Medicine, School of Medicine, Shahid Mostafa Khomeini Hospital, Ilam University of Medical sciences. ORCID iD: 0000-0002-5851-8772


| Reza Asadzadeh
Assistant Professor of Nephrology, School of Medicine, Ilam University of Medical sciences, Ilam, Iran. https://orcid.org/0000-0001-8214-9818


| Fakhredin Taghinezhad
Department of Nursing, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. ORCID ID:0000-0002-2566-5135


| Reza Mahmodzadeh
MD, School of Medicine, Ilam University of Medical sciences,


| Ali Ashraf Mozafari
Non-Communicable Diseases Center, Ilam University of Medical Sciences, Ilam Iran. Contact No: +989183432983 http://orcid.org/0000-0002-9962—3130
نشانی اینترنتی http://www.ijotm.com/ojs/index.php/IJOTM/article/view/941
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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