این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
گوارش، جلد ۲۷، شماره ۱، صفحات ۴۵-۵۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Laboratory Findings of Patients Diagnosed with Celiac Disease
چکیده انگلیسی مقاله Background: Celiac disease (CD) is an autoimmune disorder of the small intestine with a genetic predisposition. The gold standard for CD diagnosis is evaluating small bowel biopsy samples. As biopsy sampling is an invasive procedure, researchers focus on finding an alternative non-invasive test that can detect CD at an earlier stage. We aimed to investigate the laboratory finding of patients with CD to introduce new diagnostic biomarkers for this disorder. Materials and Methods : In this cross-sectional study laboratory results of 175 patients with celiac were evaluated. Subjects were analyzed through following variables: age, sex, Marsh classification, hemoglobin level, white blood cell count, platelets, eosinophil, neutrophil, lymphocytes, ferritin, liver enzymes, fat profile, iron profile, calcium, and phosphorus. SPSS software, version 22, was used for analysis. Results: 69 (39.4%) patients were men and 106 (60.6%) were women with a mean age of 34.4 years. The extraintestinal symptoms were predominant which anemia (28.6%), microcytic erythrocytes (20%) and hypochromic RBCs (26.9%) were the most laboratory findings. Hypertransaminasemia, low ferritin, hypocalcemia and leukemia was reported in 23.4%, 17.1%, 5.7% and 4.7% of patients respectively. According to the pathological classification: 23 (13.1%) patients were Marsh I, 29 (16.6%) patients Marsh II, and 118 (67.4%) patients Marsh III. Conclusion: The lack of food, vitamins and minerals can be evaluated through laboratory studies and may open the door to early detection of the disease.
کلیدواژه‌های انگلیسی مقاله Celiac disease,Laboratory study,Diagnostic test
نویسندگان مقاله | Farzaneh Mahmoudi
Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran. USERN Office, Functional Neurosurgery Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Meisam Akhlaghdoust
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Amir Sadeghi
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Mohamad Amin Pourhosseingholi
-Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran -USERN Office, Functional Neurosurgery Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Poorya Davoodi
Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Alireza Zali
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Mohammad Rostami Nejad


نشانی اینترنتی http://govaresh.org/index.php/dd/article/view/2437
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات