این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Pediatric Hematology and Oncology، جلد ۱۲، شماره ۳، صفحات ۲۰۸-۲۱۳
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی An Unfavorable Metastatic Site at Initial Diagnosis in a 2-year-old Boy with Neuroblastoma
چکیده انگلیسی مقاله Neuroblastoma (NB) is considered one of the malignant tumors of the nervous system which originates from primordial neural crest cell and is known as the most common extra-cranial solid tumor in childhood. This tumor which is often intra-abdominal, metastases in various sites including the skull, long bones, liver, bone marrow and lymph nodes, but lung metastasis at initial diagnosis is rare (0.2-3.7%). Here, the authors reported a two-year-old boy who referred to Imam Hussein Children's Hospital affiliated to Isfahan University of Medical Sciences, Iran in April 2017 with complaint of abdominal pain and distension along with diarrhea, vomiting and fever. In physical examination, a palpable mass was observed at the right side of the abdomen, that in further studies, NB with lung metastasis along with poorly differentiated, low MKI, positive MYCN amplification was reported. This is the first documented case report of NB with lung metastasis from Iran. In conclusion, although lung is considered as an unfavorable metastatic site for NB, in high grade and poor prognosis cases, this organ should also be examined in metastatic site examinations. Therefore, lung High-resolution computed tomography (HRCT) is introduced as the gold standard modality for this work.
کلیدواژه‌های انگلیسی مقاله Lung, Metastasis, MYCN Protein, Neuroblastoma
نویسندگان مقاله سعید یوسفیان | Saeed Yousofian
Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran


محمد ذوالفقاری | Mohammad Zolfaghari
Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


مریم باغ بهشتی | Maryam Baghbeheshti
Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


شادروز معظم | Shadrooz Moazzam
Student Research Committee, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran


اعظم هاشمی | Azam Hashemi
Department of Pediatrics, Hematology, Oncology Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
مرکز تحقیقات خون و انکولوژی اطفال، دانشگاه علوم پزشکی شهید صدوقی یزد، یزد، ایران

نشانی اینترنتی http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-588-1&slc_lang=en&sid=1
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده تخصصی
نوع مقاله منتشر شده گزارش مورد
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات