| چکیده انگلیسی مقاله |
Background: We aimed to investigate the epidemiological, clinical and paraclinical aspects of Visceral Leishmaniasis in Ardabil Province, from 1986 to 2018.
Methods: The disease has been diagnosed by a serological validate test as Direct Agglutination Test, parasitological methods, and clinical manifestations. The data were collected and then analyzed.
Results: Overall, 2824 out of 69007cases (4.1%) had anti-Leishmania antibodies at titers≥1:3200. The majority of VL cases belonged to Meshkin-Shahr, and then Germi County. The percentages of both male and female cases were 52.8 % and 46.6%, respectively. Approximately 78.1% of cases were less than 5 yr old. The high incidence rate of the disease was recorded in the years 1987 and 2003. 48.6%, 3.2%, and 1.9% of the patients had low titer (1:3200), high titer (1:102400), and suspicious titer (1:1600), respectively. Out of 1200 bone marrow aspiration, 23% were positive, and 77% were negative. Fever, paleness, and hepatosplenomegaly were the main symptoms in patients. Moreover, abdominal swelling, edema, weight loss, lymphadenopathy and jaundice were some other symptoms in the patients. Among biochemistry factors, the levels of aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, triglyceride and cholesterol have been increased. The death rate was estimated to be 2.8%, mainly related to the Ardabil and Germi cases.
Conclusion: Kala-Azar is still one of the most important infectious diseases in Ardabil Province, and is responsible for considerable death rate in infants. More attention should be done to parasite control and early diagnosis. |
| نویسندگان مقاله |
| Soheila Molaie
1. Zoonoses Research Center, Ardabil University of Medical Sciences, Ardabil, Iran 2. Deputy of Health, Ardabil University of Medical Sciences, Ardabil, Iran
| Hamed Zandian
Social Determinants of Health Research Center, Ardabil University of Medical Sciences, Ardabil, Iran
| Akbar Molaie
Shahid Madani Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
| Telma Zahirian
Social Determinants of Health Research Center, Ardabil University of Medical Sciences, Ardabil, Iran
| Mehdi Mohebali
1. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sci-ences, Tehran, Iran 2. Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran
| Zabih Zarei
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Babak Nakhostin
Deputy of Health, Ardabil University of Medical Sciences, Ardabil, Iran
| Dariush Emdadi
Deputy of Health, Ardabil University of Medical Sciences, Ardabil, Iran
| Behnaz Akhoundi
1. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sci-ences, Tehran, Iran 2. Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran
| Seyyedeh-Negar Modares-Sadrani
Deputy of Health, Ardabil University of Medical Sciences, Ardabil, Iran
| Hamed Abdollahzadeh
Deputy of Health, Ardabil University of Medical Sciences, Ardabil, Iran
| Zahra Rakhshidan
Deputy of Health, Ardabil University of Medical Sciences, Ardabil, Iran
| Ezat Ezati
Deputy of Health, Ardabil University of Medical Sciences, Ardabil, Iran
| Zahra Heidari
Department of Medical Parasitology and Microbiology, Ardabil University of Medical Sciences, Ardabil, Iran
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