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Middle East Journal of Digestive Diseases، جلد ۱۴، شماره ۳، صفحات ۳۲۳-۳۲۹

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عنوان انگلیسی The Effect of Gluten-Free Diet Duration on Body Mass Index of Iranian Patients with Celiac Disease
چکیده انگلیسی مقاله BACKGROUND: A gluten-free diet (GFD) is the only effective treatment of celiac disease (CD) that is associated with body mass index (BMI) changes. This study aimed to determine how GFD duration affects the BMI of Iranian patients with CD. METHODS: In this prospective study, 215 patients with CD, who were on a GFD, were categorized into three groups according to the duration of compliance to GFD: 1. patients with less than 6 months of diet, 2. Patients who had a diet for 6 months to 2 years, and 3. patients with more than 2 years of diet. The BMI changes were assessed before and after adherence to the GFD. RESULTS: Most patients’ weight remains in the same BMI category during different courses of GFD adherence. Patients who were underweight showed significant changes in their BMI following the diet in less than 6 months ( P = 0.033) and more than 2 years ( P < 0.001), and the number of weight gain cases increased over time. CONCLUSION: There is a need for careful, updated, and personalized nutrition management of patients with CD in different periods of the diet. Conducting similar studies with larger sample sizes in different regions can lead to providing expert dietary counseling for patients with CD.
کلیدواژه‌های انگلیسی مقاله Celiac disease, gluten, gluten free diet, body mass index

نویسندگان مقاله | Nastaran Asri
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Nazanin Taraghikhah
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Reyhaneh Baniasadi
Dudley Group of Hospitals NHSF Trust, UK.


| Sauid Ishaq
Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Mostafa Rezaei-Tavirani
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Amir Sadeghi
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Mohammad-Javad Ehsani-Ardakani
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Somayeh Jahani-Sherafat
Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Hamid Asadzadeh Aghdaei
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Mohammad Rostami-Nejad



نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/2604
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