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Iranian Journal of Blood and Cancer، جلد ۱۴، شماره ۲، صفحات ۵۸-۶۰
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عنوان انگلیسی Unusual ophthalmic manifestation in chronic myeloid leukemia: A case report
چکیده انگلیسی مقاله Background: Chronic myeloid leukemia (CML) is a myeloproliferative hematopoietic malignancy with a heterogeneous proliferation of hematopoietic cells in the bone marrow. The ocular manifestations are rare symptoms of CML. In this case report, a CML patient with retinal hemorrhage is reported as an uncommon symptom. Case presentation: A 35-year-old man was referred due to decreased right eye vision. The reduction of the visual acuity of the right eye (2/10), rounded and diffuse intra-retinal hemorrhage with white-center Roth's spots, and macular edema were seen. No systemic diseases and other ophthalmic manifestations were seen in this case. The white blood cell (WBC) count was 135,000 cells/ μl, the platelets were 430,000 cells/μl, and hemoglobin was 12.5 gr/dl. The myeloid progenitor and precursor were present in peripheral blood smear and bone marrow. Also, the quantitative real-time polymerase chain reaction indicated that the BCR-ABL1-to-ABL1 ratio was 0.795. a daily administration of 400 mg of Imatinib was prescribed. Two months later, WBC count reached 6,500 cells/μl, Hb was 11.6 gr/dl, and platelets were 306,000 cells/μl. Conclusion: The ophthalmic manifestations may be a symptom of CML. We found the rounded and diffuse intra-retinal hemorrhage, Roth's spots, and macular edema as the ocular manifestation of a CML case.
کلیدواژه‌های انگلیسی مقاله Chronic myeloid leukemia, Visual acuity, Roth&apos,s spots, Ophthalmic manifestations
نویسندگان مقاله | Mohsen Vakili
School of Medicine, Babol University of Medical Sciences, Babol, Iran.


| Seyed Ahmad Rasoulinejad
Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-731-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Adults Hematology & Oncology
نوع مقاله منتشر شده گزارش مورد
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