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Journal of Family and Reproductive Health، جلد ۱۶، شماره ۳، صفحات ۱۷۷-۱۸۲
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عنوان انگلیسی Comparative Analytical Study of Dinoprostone Gel and Hyaluronidase Injection for Induction of Labour in Term Primigravida in Tertiary Rural Medical Centre of Western Uttar Pradesh
چکیده انگلیسی مقاله Objective: To compare the efficacy of intracervical dinoprostone gel and hyaluronidase injection for induction of labour in term primigravida. Materials and methods: This is a hospital based analytical prospective interventional study conducted in a rural tertiary care centre over a period of 18 months.  A total of 70 patients who required induction of labour for one or another reason with Bishop score of less than 6 were included in the study. All the cases were randomly divided into two groups, Group A received dinoprostone gel and Group B received hyaluronidase injection. Chi square test & unpaired T test were applied for statistical analysis. Results: Time interval from induction to active phase of labour was comparatively shorter in group A than in group B (10.74 ± 6.17 vs 15.94 ± 7.1) and the difference was significant (p= 0.001). Time interval from induction to delivery time was comparatively shorter in group A than group B (14.84 ± 8.86 vs 21.33 ± 7.86) and difference was significant (P= 0.009). Maternal complications were more common in group A as compared to group B. Conclusion: This study showed that labour could be accelerated significantly by intracervical injection of hyaluronidase. Hyaluronidase injection has less maternal and fetal side-effects as compared to dinoprostone gel and can be a good choice for induction of labour.
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نویسندگان مقاله | Neelam Swaroop
T.S. Mishra Medical College Lucknow, Uttar Pradesh, India


| Shaheen Bano
Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India


| Soniya Vishwakarma
Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India


| Nupur Mittal
Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India


| Vaibhav Kanti
Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India


| Vandana Gupta
Rajarshi Dashrath Autonomous State Medical College, Ayodhya, Uttar Pradesh, India


| Pragya Shree
Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
نشانی اینترنتی https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2043
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