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International Journal of Organ Transplantation Medicine، جلد ۱۳، شماره ۲، صفحات ۰-۰
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عنوان انگلیسی Current Situation and Prognostic Evolution of Combined Heart-lung Transplantation in a European :union: Country
چکیده انگلیسی مقاله Background: This study aims to evaluate the entire experience in heart-lung transplantation (HLTx) in a country of the European :union: with 47 million inhabitants according to the etiologies that motivated the procedure. Methods: A retrospective study on 1,751 consecutive transplants (HLTx: 78) was performed from 1990 to 2020 in two centers. Overall survival, adjusted for clinical profile and etiological subgroups, was compared. 7 subgroups were considered: 1) Cardiomyopathy with pulmonary hypertension (CM + PH). 2) Eisenmenger syndrome. 3) Congenital heart disease (CHD). 4) Idiopathic pulmonary arterial hypertension (IPAH). 5) Cystic fibrosis. 6) Chronic obstructive pulmonary disease (COPD)/Emphysema. 7) Diffuse interstitial lung disease (ILD). Results: Early mortality was 44% and that of the rest of the follow-up was 31%. There were differences between HTLx and HTx in survival, also comparing groups with a similar clinical profile with propensity score (p= 0.04). Median survival was low in CM + PH (18 days), ILD (29 days) and CHD (114 days), intermediate in Eisenmenger syndrome (600 days), and longer in IPAH, COPD/Emphysema and cystic fibrosis. Conclusion: HLTx has a high mortality. The etiological analysis is of the utmost interest to make the most of the organs and improve survival.
کلیدواژه‌های انگلیسی مقاله Heart-lung transplantation,Heart transplantation,Survival,Etiology
نویسندگان مقاله | Raquel López-Vilella
Department of Transplantation, Shiraz University of Medical Sciences, Shiraz


| M. Gómez Bueno


| F. González Vílchez


| L. Almenar Bonet


نشانی اینترنتی http://www.ijotm.com/ojs/index.php/IJOTM/article/view/1052
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