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Iranian Journal of Blood and Cancer، جلد ۱۴، شماره ۳، صفحات ۳۲-۴۰
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عنوان انگلیسی Overview on Evans syndrome: In the course of Covid-19 pandemic; essentials and approaches
چکیده انگلیسی مقاله Redundant studies proved coronavirus infection results from a defect in a suitable immune response that may exacerbate immune-inflammatory reactions like cytokine storm and autoimmunity. Evans syndrome (ES) is a rare chronic autoimmune disease that distinguishes it from autoimmune hemolytic anemia (AIHA) and immune thrombocytopenic purpura (ITP). Reports have shown significant differences in immune cells and laboratory parameters in Evans syndrome/COVID-19 co-infected patients. Also, the contribution between autoimmune diseases and SARS-CoV-2 infection could result in immune response disequilibrium that considers a possible mechanism for ES development. Moreover, we will briefly explain the double-edged sword role of immunosuppressive drugs in Evans syndrome/COVID-19 co-infected patients. Generally, the pathophysiology of SARS-CoV-2 in hematologic autoimmune disorders progression, particularly ES, remains unclear, but some investigations explain the COVID-19 infection mechanism in the mentioned disorders development. The purpose of the current study is to look at the coronavirus effects on Evans syndrome aggravation, the immune cells and laboratory markers alterations in Evans syndrome/COVID-19 co-infected patients, the coronavirus effects on Evans syndrome patients during their pregnancy, and the Evans syndrome / COVID-19 co-infected patient management.
کلیدواژه‌های انگلیسی مقاله Coronavirus, COVID-19, Evans syndrome, Autoimmune disease, SARS-CoV-2
نویسندگان مقاله | Gholamhossein Tamaddon
Shiraz Medical Sciences


| Pooria Fazeli
Shiraz Medical Sciences


| mohammadreza saeidnia
Shiraz Medical Sciences


| Arghavan Farzi
Ilam Medical Sciences


| Navid Pooresmaeil
Ilam Medical Sciences


| Mohammad hamed Javanmardi
Shiraz Medical Sciences
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-570-2&slc_lang=fa&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده fa
موضوعات مقاله منتشر شده Immunology
نوع مقاله منتشر شده مقاله مروری
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