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The Archives of Bone and Joint Surgery، جلد ۱۰، شماره ۶، صفحات ۴۹۰-۵۰۰
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عنوان انگلیسی The Perioperative Management of Antiplatelet and Anticoagulant Drugs in Hip Fractures: Do the Surgery as Early as Possible
چکیده انگلیسی مقاله Hip fractures are among the most common fractures operated by orthopedic surgeons. Many elderly patients, who account for a significant percentage of hip fractures, suffer from medical conditions requiring antiplatelet and anticoagulant administration. Meanwhile, considerable evidence recommends early surgery within 48b hours of admission. We aim to review the existing evidence regarding the perioperative management of antiplatelet and anticoagulant drugs in hip fractures. It was concluded that surgery for hip fractures in patients with antiplatelet drug consumption should not be delayed unless a clear contraindication exists. Active reversal strategies are indicated for patients with hip fractures and warfarin therapy. However, evidence for the safety of these agents in pregnancy, breastfeeding state, and adolescence has not yet been established. Little data exists about perioperative management of direct-acting oral anticoagulants in hip fractures. Early surgery after 12-24 hours of drug cessation has been suggested in studies; however, it should be employed cautiously. Despite extensive research, the importance of the issue necessitates additional higher-quality studies.Level of evidence: V
کلیدواژه‌های انگلیسی مقاله Anticoagulant, Antiplatelet agent, Hip fracture, perioperative management, Vitamin K antagonists
نویسندگان مقاله | Mohammad Ali Ghasemi
Joint Reconstruction Research Center, Tehran University of Medical Science, Tehran, Iran


| Ehsan Ghadimi
Joint Reconstruction Research Center, Tehran University of Medical Science, Tehran, Iran


| Ahmad Shamabadi
1 Joint Reconstruction Research Center, Tehran University of Medical Science, Tehran, Iran 2 School of Medicine, Tehran University of Medical Science, Tehran, Iran


| SM Javad Mortazavi
Joint Reconstruction Research Center, Tehran University of Medical Science, Tehran, Iran
نشانی اینترنتی https://abjs.mums.ac.ir/article_18884.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده CURRENT CONCEPTS REVIEW
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