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Iranian Journal of Otorhinolaryngology، جلد ۳۴، شماره ۴، صفحات ۱۵۷-۱۶۴
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عنوان انگلیسی Prognostication of Sino-Nasal Mucormycosis
چکیده انگلیسی مقاله Introduction: For the purpose of prognostication of sinonasal mucormycosis, a detailed analysis of the clinical, diagnostic, therapeutic and outcome parameters has been contemplated. Materials and Methods: Retrospectively data was collected for all patients of sinonasal mucormycosis managed in a tertiary care hospital in last 5years. Results: Diabetes was the commonest comorbidity among total of 52 cases. Disease extent-wise, 16, 23 and 13 patients had sino-nasal (SN), rhino-orbital (RO) and rhino-orbito-cerebral (ROC) mucormycosis respectively. Median cumulative Amphotericin-B administered was 3.5gms and 94.2% of cases underwent surgical debridement depending on the disease extent. With a median follow-up of 18months, 67% of the patients are alive and disease free, 2% are under treatment and 29% of patients have expired. The mortality rate was 12.5% in SN, 30.5% in RO and 38.5% in ROC mucormycosis. Palatal and orbital involvement is associated with statistically significant mortality risk at one month. Conclusions: Mortality rate in sino-nasal mucormycosis can be significantly curtailed with prompt control of underlying comorbidity, aggressive medical and adequate surgical management.
کلیدواژه‌های انگلیسی مقاله Amphotericin, Diabetes, Mucormycosis, Sino nasal Mucormycosis, Orbital mucormycosis
نویسندگان مقاله | Prem Sagar
Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.


| Namrita Mehmi
Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.


| Anupam Kanodia
Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.


| Avinash Jaiswal
Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.


| Rajeev Kumar
Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.


| Chirom Singh
Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.


| Rakesh Kumar
Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.


| Alok Thakar
Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.
نشانی اینترنتی https://ijorl.mums.ac.ir/article_20594.html
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