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Iranian Journal of Medical Sciences، جلد ۴۷، شماره ۵، صفحات ۴۵۰-۴۶۰

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عنوان انگلیسی Predictors of Intensive Care Unit Admission in Patients with Confirmed Coronavirus Disease 2019: A Cross-Sectional Study
چکیده انگلیسی مقاله Background: The coronavirus disease 2019 (COVID-19) has become the leading source of pneumonia outbreaks in the world. The present study aimed to compare the condition of intensive care unit (ICU) and non-ICU COVID-19 patients in terms of epidemiological and clinical features, laboratory findings, and outcomes in three cities across Iran.Methods: In a cross-sectional study, 195 COVID-19 patients admitted to five hospitals across Iran during March-April 2020 were recruited. Collected information included demographic data, laboratory findings, symptoms, medical history, and outcomes. Data were analyzed using SPSS software with t test or Mann-Whitney U test (continuous data) and Chi square test or Fisher’s exact test (categorical variables). P< 0.05 was considered statistically significant.Results: Of the 195 patients, 57.4% were men, and 67.7% had at least one comorbidity. The prevalence of stroke, chronic obstructive pulmonary disease, and autoimmune diseases was higher in ICU than in non-ICU patients (P=0.042, P=0.020, and P=0.002, respectively). Compared with non-ICU, ICU patients had significantly higher white blood cell (WBC) count (P=0.008), cardiac troponin concentrations (P=0.040), lactate dehydrogenase levels (P=0.027), erythrocyte sedimentation rates (P=0.008), and blood urea nitrogen (BUN) (P=0.029), but lower hematocrit levels (P=0.001). The mortality rate in ICU and non-ICU patients was 48.1% and 6.1%, respectively. The risk factors for mortality included age>40 years, body mass index< 18 Kg/m2, hypertension, coronary artery disease, fever, cough, dyspnea, ST-segment changes, pericardial effusion, and a surge in WBC and C-reactive protein, aspartate aminotransferase, and BUN. Conclusion: A high index of suspicion for ICU admission should be maintained in patients with positive clinical and laboratory predictive factors.
کلیدواژه‌های انگلیسی مقاله COVID-19, SARS-CoV-2, Dyspnea, Pneumonia, Intensive care unit

نویسندگان مقاله Naeimehossadat Asmarian |
Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Farid Zand |
Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Parvin Delavari |
Nursing Care Research Center, School of Nursing and Midwifery, Semnan University of Medical Sciences, Semnan, Iran

Vahid Khaloo |
Hazrate Ali-Asghar Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

Zahra Esmaeilinezhad |
Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Golnar Sabetian |
Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Yaldasadat Moeini |
Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Mohsen Savaie |
Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Fatemeh Javaherforooshzadeh |
Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Farhad Soltani |
Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Farid Yousefi |
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Ebrahim Heidari Sardabi |
Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Maryam Haddadzadeh Shoushtari |
Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Anoush Dehnadi Moghadam |
Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran

Fatemeh Dehnadi Moghadam |
Aachen Faculty of Medicine, Aachen, North Rhine-Westphalia, Germany

Somayeh Gholami |
Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran


نشانی اینترنتی https://ijms.sums.ac.ir/article_48348_9e2130ffba68a86e35ce0964a81e114a.pdf
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