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Caspian Journal of Enviromental Sciences، جلد ۲۰، شماره ۳، صفحات ۵۶۵-۵۷۰
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عنوان انگلیسی Evaluating the efficacy of flavonoids from Capparis spinosa extracts in treatment of Candida vulvovaginitis
چکیده انگلیسی مقاله Flavonoids were extracted from the leaves and stems of the Capparis spinosa (Caper) plant. The total flavonoids were detected with qualitative and quantitative assays. C. albicans isolates were isolated from patients infected with vaginal candidiasis and these fungal isolates revealed high levels of biofilm formation. Flavonoids isolated from the leaves and stems of the C. spinosa plant were found to have antibiofilm activity against all C. albicans isolates dependent on dose manner. In comparison to the control, flavonoids influence all C. albicans, at 400 µg mL-1, with percentages of biofilm inhibition ranging from 69 to 31%. These findings imply that flavonoids could be useful in treating biofilm-associated C. albicans infections to overcome the difficulties associated with multi-antibiotic resistance.
کلیدواژه‌های انگلیسی مقاله Capparis spinose, Candida vulvovaginitis, Flavonoids
نویسندگان مقاله Majd Dameh |
FATIMA College of Health Sciences Abu Dhabi, UAE

Abeer Ameen Baqer |
Medical Laboratory Techniques Department, Dijlah University College, Iraq, Baghdad

Muhaned Zaidi |
Al-Manara College for Medical Sciences, Maysan, Iraq

Safa K. Hachim |
College of Technical Engineering, The Islamic University, Najaf, Iraq

Noora M. Hameed |
Anesthesia techniques, Al–Nisour University College, Iraq

Sura A. Awadh |
Department of Anesthesia, Al-Mustaqbal University, Babylon, Iraq

Ali Jalil Obaid |
Medical Laboratory Techniques Department, Hilla University College, Babylon, Iraq

Zainab Hussein Adhab |
Department of Pharmacy, Al-Zahrawi University College, Karbala, Iraq

نشانی اینترنتی https://cjes.guilan.ac.ir/article_5692_4cdf57006c4e60410cf9c1788cc70f80.pdf
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