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Journal of Nanostructures، جلد ۱۰، شماره ۴، صفحات ۸۱۷-۸۲۴
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عنوان انگلیسی Cu- Zeolitic Imidazolate Framework-8 Loaded on Magnetic Nanofiber as a High-efficient Antimicrobial Scaffold
چکیده انگلیسی مقاله In this work, CoFe2O4 was synthesized as magnetic agent and blended with chitosan-poly vinyl alcohol (CS-PVA) to fabricate magnetic nanofiber (MNF) by electrospinning method. Zeolitic imidazolate framework-8 (ZIF-8) crystals were used as a porous media to prepare MNF@ZIF-8 nanocomposite. Two different methods were employed for doping copper ions into the MNF@ZIF-8 structure by adsorption and encapsulation procedures. Characterization clarification of as synthesis materials were performed. Mechanical tests showed that magnetic nanoparticles caused to improve tension resistance of CS-PVA nanofibrous scaffold. Antimicrobial tests for the prepared materials were done in against two types of Gram-positive and Gram-negative strains. The inhibition zone diameter values for Cu2+ adsorbed-MNF@ZIF-8 (33 mm and 24 mm for E.coli and S.aureus, respectively) were better than that of Cu2+ encapsulated-MNF@ZIF-8 (32 mm and 18 mm for E.coli and S.aureus, respectively). The obtained results showed that the prepared copper doped MNF@ZIF-8 can be potentially used as a scaffold for further investigations in practical wound healing applications.
کلیدواژه‌های انگلیسی مقاله Metal organic framework, Cu-doped ZIF-8, magnetic nanofiber, Nanocomposite, Chitosan-PVA, Antibacterial Activity
نویسندگان مقاله Jafar Abdi |
Faculty of Chemical and Material Engineering, Shahrood University of Technology, Shahrood, Iran

نشانی اینترنتی https://jns.kashanu.ac.ir/article_110815_3884a029c2da5a0dcbd8b7a77aad3910.pdf
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