این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Research in Medical Sciences، جلد ۲۸، شماره ۲۸، صفحات ۲۰۲۳-۲۸
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی High amylase concentration in drainage liquid can early predict proximal and distal intestinal anastomotic leakages A prospective observational study
چکیده انگلیسی مقاله Background: Anastomotic leak (AL) is a serious complication in digestive surgery. Early diagnosis might allow clinicians to anticipateappropriate management. The aim of this study was to assess the predictive value of amylase concentration in drain fluid for the early diagnosis of digestive tract AL. Materials and Methods: Hundred and fourteen consecutive patients “at isk” of AL, in whom a flexible drainage was placed by surgeon’s choice after digestive anastomosis were included. Patients with eso?gastric, bilio?digestive, and pancreatic anastomoses were excluded. Drain mylase measurement (DAM) was routinely performed on postoperative ay (POD) 1, 3, 5–7. DAM values were compared between patients with postoperative AL versus patients without AL. A receiver?operating curve (ROC) with calculation of the areas under the ROC curves area under curves was performed and a cutoff value of DAM was calculated. Results: AL occurred in 25 patients (AL group) and 89 patients did not present AL (C group). The mean DAM was significantly higher in AL group versus C Group on POD 1, 3, and 5. A cutoff value of 307 IU/L predicted the occurrence of AL with a sensitivity and specificity of 91% and 100%, respectively. Positive and negative predictive values were 100% and 97.5%, respectively. Patients with AL had an elevated DAM prior to the appearance of any clinical signs of AL. Conclusion: High level DAM acould accurately predict AL for proximal and distal digestive tract anastomoses. This simple, noninvasive, and low?cost method can accurately predict early AL and help physicians to perform appropriate imaging and treatment.
کلیدواژه‌های انگلیسی مقاله Amylase, anastomotic leakage, digestive anastomosis, drain fluid
نویسندگان مقاله | Koceila Amroun


| Zoubir Djerada


| Laurent Ramont


| Cyril Perrenot


| Linda Rached


| Yohan Renard


| Rami Rhaiem


| Reza Kianmanesh


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/11403
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات