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Iranian Journal of Medical Physics، جلد ۲۰، شماره ۲، صفحات ۱۰۰-۱۰۵
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عنوان انگلیسی Quantitative Analysis of Parotid Sparing and Reducing Xerostomia Using Volumetric Modulated Arc Therapy in Oral Cancer Patients
چکیده انگلیسی مقاله Introduction: In head and neck cancer (HNC) radiotherapy, parotid, submandibular, and minor salivary glands are often incidentally irradiated. Hence, Xerostomia is the most significant disabling side-effect, to improve the quality of life, it should be reduced. The study was to evaluate the parotid dose and PTV coverage in post operated Oral cancer patients using Volumetric Modulated Arc Therapy (VMAT) technique. Material and Methods: The authors generated VMAT plans for 14 post operated oral cancer patients, where primary disease crossed midline or nodal stage ≥ 2. The doses to the moderate high-risk volume of the clinical target volume (CTV) and planning target volume (PTV) were 60Gy in 30 fractions. The low-risk volume received a dose to the CTV and PTV of 54Gy in 30 fractions. Plans were made for each patient, and the dose to D95 and D98 of target volumes was analyzed. The mean dose of the parotid and parotid minus PTV volumes were analyzed and compared with target doses (D98 & D95). Results: Median dose to the ipsilateral parotid gland was 54.45Gy and to the ipsilateral parotid gland minus PTV was 45.60Gy while to the contralateral parotid gland median dose was 16.31Gy, (mean is ranging from 14.01 to 17.06Gy) and to the contralateral parotid gland minus PTV was 14.92 (mean is ranging from 12.42 to 15.18Gy) after achieving the 95% coverage of PTV. Conclusion: Better sparing of contralateral parotid glands with the help of VMAT technique in post-operative HNC patients is possible, which can prevent xerostomia in most patients. 
کلیدواژه‌های انگلیسی مقاله Parotid, Xerostomia, oral cancer
نویسندگان مقاله | PALANIVELU D
Radiation Oncology Department, Fortis Hospital,Mohali,Punjab,India.


| Mohandass P
Chief Medical Physicist Department of Radiation Oncology Fortis Hospital Sector 62, Phase 8, SAS Nagar Moahli-160062 Punjab India


| Debashis Panda
Department of Radiation Oncology, LHDM & Dr. Prem Hospital, Panipat, Haryana


| Narendra Kumar Bhalla
Department of Radiation oncology Fortis Hospital Sector 62, Phase 8 SAS Nagar Mohali - 160062 Punjab, India


| KHANNA D
Department of Physics, School of Sciences, Arts, Media and Mangement, Karunya Institute of Technology and Sciences, Coimbatore-641 114 Tamilnadu India


| Susan Abharam
Department of Radiation Oncology Medanta The Medicity Gurgoan Haryana


| abhishek Puri
Department of Radiation Oncology Fortis Hospital Sector 62, Phase 8 SAS Nagar Mohali - 160062 Punjab, India


| Manoharan M
Department of Radiation Oncology Fortis Hospital, Sector 62, Phase 8, SAS Nagar, Mohali - 160062 Punjab, India
نشانی اینترنتی https://ijmp.mums.ac.ir/article_20257.html
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نوع مقاله منتشر شده Original Paper
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