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Journal of Craniomaxillofacial Research، جلد ۹، شماره ۳، صفحات ۱۱۸-۱۳۱
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عنوان انگلیسی The relationship between anosmia and ageusia with biochemical markers, severity, and duration of the disease in patients with COVID-19
چکیده انگلیسی مقاله Introduction: Due to the increasing prevalence of COVID-19 and its effects on the sense of taste and smell, we analyzed Blood electrolyte levels and biomarkers in COVID-19 patients who have a sign of anosmia and ageusia in Zanjan, Iran, and its relationship with biochemical blood indicators. Materials and Methods: The retrospective study included all hospitalized patients with confirmed COVID-19. We registered laboratory parameters. A questionnaire that validity and reliability have already been confirmed was used to assess anosmia and ageusia. Statistical analysis was evaluated using a bivariate Bayesian logistic regression in the binomial distribution. Results: A total of 450 COVID-19 patients completed the study (221 females). The mean age of the patients was 56.36±17.34 years. 31.8% and 24.9% of patients reported anosmia and ageusia. There was no significant relationship between anosmia and ageusia with age, gender, place of hospitalization, marriage status, duration of hospitalization, and CT scan (p< 0.05). The Male’s platelet was 18.72 lower than the female’s (p=0.002). Male’s C-reactive protein was 4.96 units higher than female (p=0.002). In hospitalized persons for less than four days and people under 39 years of age, CRP levels were lower (P=0.001, P=0.019 respectively). The Levels of lactate dehydrogenase in patients with anosmia were 51.72 units less than in patients without anosmia (p=0.010). Conclusion: These results suggest that anosmia and ageusia are prevalent symptoms in Iranian COVID-19 patients. More information on serum biomarkers would help us to establish a greater degree of accuracy on this matter. Keywords: COVID-19; Anosmia; Ageusia; C-reactive protein; Lactate dehydrogenase.
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نویسندگان مقاله | Ahmadreza Rasouli
Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.


| Mashhoud Taghiloo
Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.


| Hamid Khederlou
Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.


| Fatemeh Moradi
Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.


| Zahra Rostami
Student Research Committee, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.


| Mohammad Jafarzadeh
Department of Infectious Diseases, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.


| Houshang Bavandpour Karvane
Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.


| Karim Parastouei
Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
نشانی اینترنتی https://jcr.tums.ac.ir/index.php/jcr/article/view/426
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