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Iranian Journal of Public Health، جلد ۴۵، شماره ۱۱، صفحات ۱۴۶۵-۱۴۷۲
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عنوان انگلیسی Various Effects of Omega 3 and Omega 3 Plus Vitamin E Supplementations on Serum Glucose Level and Insulin Resistance in Patients with Coronary Artery Disease
چکیده انگلیسی مقاله Background: Omega 3 and vitamin E are two critical nutrients which include beneficial effects in coronary artery disease (CAD). The aim of this study was to assess the effects of omega 3 alone supplementation or in combination with vitamin E on serum glucose and lipid levels and insulin resistance in CAD patients. Methods: Participants of this clinical trial included 60 male patients with CAD who selected from Tehran Heart Center in Tehran, Iran in 2014. They received 4 g/day omega 3 plus 400 IU/day vitamin E (OE), 4 g/day omega 3 with vitamin E placebo (OP), or omega 3 and vitamin E placebo (PP) for two months. Serum glucose, lipids and insulin were assessed and HOMA-IR was calculated before and after the trial and effects of these nutrients on the highlighted parameters were compared within the study groups. Results: Serum glucose level increased significantly in OP group ( P =0.004), but not in OE group. OE and OP groups showed a significant decrease in fasting serum TG ( P =0.020 and P =0.001, respectively). Serum insulin and HOMA-IR decreased significantly in OE group ( P =0.044 and P =0.039, respectively) but did not change significantly in OP group. Conclusion: Although, omega 3 supplementation may include adverse effects on serum glucose level, co-administration of omega 3 and vitamin E can beneficially decrease serum insulin and insulin resistance in CAD patients.
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نویسندگان مقاله سمیه صبوری | somayeh saboori


محمود جلالی | mahmoud djalali


اسماعیل یوسفی راد | esmaeil yousefi rad


ابراهیم نعمتی پور | ebrahim nematipour


علی اکبر صبور یراقی | ali akbar saboor yaraghi


محمد حسن جوانبخت | mohammad hassan javanbakht


محمد رضا اشراقیان | mohammad reza eshraghian


آتنا رمضانی | atena ramezani


فریبا کوهدانی | fariba koohdani


نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/8348
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/86/article-86-269884.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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