این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Physiology and Pharmacology، جلد ۲۷، شماره ۱، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Umbilical cord as a source of mesenchymal stem cells improves melasma in parturients: a clinical randomized trial
چکیده انگلیسی مقاله ABSTRACT Introduction: Melasma is a common skin problem in pregnant women that appears to be related to physiological changes. Mesenchymal stem cells (MSCs) have been used to treat skin disorders because of their direct cell-to-cell contact or release of several biomolecules. The umbilical cord, which is available at birth, has been shown to be a rich source of MSCs. This study was undertaken to evaluate the effect of the umbilical cord as a natural face mask for treating women's melasma after parturition. Methods: This randomized clinical trial was carried out on parturients suffering from melasma. Fifty pregnant women were randomly categorized into two groups of control and treated with the umbilical cord. A section of the umbilical cord (10-20 cm) was cut immediately after parturition and used as a face mask on the face of each mother in the hyperpigmentation areas for one hour. Melasma Area Severity Index (MASI) was used to measure hyperpigmentation and calculated for each participant before and four weeks after intervention. Results: A significant decrease in MASI was observed in the women treated with the umbilical cord (p< 0.05). Conclusion: Our findings suggested that a fresh umbilical cord, as a natural face mask containing MSCs, can improve the melasma in the parturients.
کلیدواژه‌های انگلیسی مقاله Umbilical cord, Mesenchymal stem cells, Pregnancy
نویسندگان مقاله | Maryam Adelipour
Department of Biochemistry, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran


| Hanan Sorkheh
Abadan University of Medical Sciences, Abadan, Iran


| Zohreh Kiani
Faculty of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran


| Houria Bahrami
Abadan University of Medical Sciences, Abadan, Iran


| Neda Berageah
Faculty of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran


| Anayat Salimi
Department of Pharmaceutics, Faculty of pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.


| Mahshid Naghashpour
Department of Nutrition, School of Medicine, Abadan University of Medical Science, Abadan, Iran


| Atefeh Zahedi
Asadabad school of medical sciences, Asadabad, Iran


| Sahar Golabi
Department of Medical Physiology, School of Medicine, Abadan University of Medical Science, Abadan, Iran
نشانی اینترنتی http://ppj.phypha.ir/browse.php?a_code=A-10-1596-1&slc_lang=en&sid=1
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Blood and Immune System
نوع مقاله منتشر شده Experimental research article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات