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Journal of Craniomaxillofacial Research، جلد ۳، شماره ۴، صفحات ۲۴۱-۲۴۷

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عنوان انگلیسی A comparative evaluation of outcomes between tongue SCC and ACC of salivary glands: retrospective match-case study
چکیده انگلیسی مقاله Introduction : The aim of this study was to assess Tongue Squamous Cell Carcinoma (TSCC) patients’ outcome and compare that to their matched pair counterparts of salivary gland adenoid cystic carcinoma (SGACC) patients. Materials and Methods : A population-based cohort study was conducted using SEER data. From a database of 2019 patients, treated from 2004 to 2012. We matched individuals with tongue SCC to those who have ACC of salivary gland. Matches were made for gender, age and treatment modalities. We compared their 5-year survival, rate of local, regional and distant failures. Results : We identified 1716 patients with TSCC and 313 cases with SGACC. Median follow up time was 2.07 years. The frequency of SGACC was significantly high in female likewise the frequency of TSCC in males (p≤0.001). SGACC tumor was more likely to be detected at an advanced stage (p≤0.001). The most often affected subsites in the TSCC tumor were the tongue (C02.9) (24.5%) and in SGACC tumor were the minor salivary gland (42.5%). There was a significant (P≤0.001) difference in overall survival in favor of female with SGACC and the combined-therapy group over the TSCC patients belong to the same group. The Kaplan–Meier estimates of overall survival at five years were 58% in the TSCC patients and 87% in the SGACC group. Conclusion : It is important for the clinicians be aware of the invasive nature of oral malignancies especially TSCC and SGACC. These lesions are associated with high recurrence rate and distant metastasis and poor prognosis. Early detection may enhance the survival rate of the patients. The overall survival is lower in TSCC than SGACC and the death rate is higher in these kinds of tumors. Key words : Diagnostics, Salivary glands, Cancer and pre-cancer, Squamous cell carcinoma.
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نویسندگان مقاله فریدون پوردانش | fereydoun pourdanesh
department of oral and maxillofacial surgery, faculty of dentistry, shahid beheshti university of medical sciences, evin, daneshjou blvd, koodakyar ave. tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

سحر مسعودی | sahar masoudi
department of biostatistics, university of social welfare and rehabilitation sciences, evin, daneshjou blvd, koodakyar ave. tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم بهزیستی و توانبخشی (University of social welfare and rehabilitation sciences)

محمد اسمعیلی نژاد | mohammad esmaeelinejad
department of oral and maxillofacial surgery, faculty of dentistry, shahid beheshti university of medical sciences, evin, daneshjou blvd, koodakyar ave. tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

رضا تبریزی | reza tabrizi
department of oral and maxillofacial surgery, faculty of dentistry, shahid beheshti university of medical sciences, evin, daneshjou blvd, koodakyar ave. tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)


نشانی اینترنتی http://jcr.tums.ac.ir/index.php/jcr/article/view/107
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/364/article-364-270216.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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