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Middle East Journal of Cancer، جلد ۱۴، شماره ۲، صفحات ۳۲۳-۳۲۶
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عنوان انگلیسی Clear Cell Adenocarcinoma of the Cervix in a Young Woman without Exposure to Diethylstilbestrol: A Case Report
چکیده انگلیسی مقاله Clear cell carcinoma is believed to be one of the rare neoplasms of cervix uteri and vagina. The etiology and pathogenesis of clear cell carcinoma of the cervix are unclear, with scarce information about the clinical behavior, optimal management, and prognosis of the tumor. The current treatment options are based on the experiences accumulated on squamous cell carcinoma and other types of adenocarcinoma. Prior intrauterine exposure to diethylstilbestrol (DES) is presumed to be a predisposing factor for clear cell adenocarcinoma in young patients. Metastasis is uncommon, but local recurrence may occur. The cure rate of this disease is 85%-90% in early stages with a small volume of tumors. In this study, we report a rare case of clear cell carcinoma of the cervix in a 21-year-old woman, who had no exposure to DES (in-utero) or synthetic non-steroidal estrogen; therefore, the present research supports the hypothesis that the risk factors, other than DES exposure, play an important role in carcinogenesis.
کلیدواژه‌های انگلیسی مقاله Adenocarcinoma, Clear cell, Diethylstilbestrol, Cervix uteri
نویسندگان مقاله Helena Azimi |
Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Malihe Hassanzadeh |
Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Seyede Sepideh Hosseini |
Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Fatemeh Homaee Shandiz |
Department of Radiotherapy, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

Amir Hossein Jafarian |
Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Afrooz Azad |
Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

نشانی اینترنتی https://mejc.sums.ac.ir/article_48774_62c8c8954f5b48bc6f44990cab5cf9ff.pdf
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