این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Dental Research Journal، جلد ۲۰، شماره ۴، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Investigation of the antifungal effects of curcumin against nystatin‑resistant Candida albicans
چکیده انگلیسی مقاله Background: Emergence of nystatin‑resistant Candida albicans (C. albicans) strains has raised some concerns in the recent years. Recent scientific evidence proves that turmeric, especially curcumin, has anti‑inflammatory and anti‑fungal activity. The aim of this study was the investigation of the antifungal effects of curcumin against nystatin‑resistant C. albicans. Materials and Methods: This in vitro, experimental study evaluated standard‑strain (ATCC 16201) and 10 nystatin‑resistant C. albicans strains. The antifungal activity and minimum inhibitory concentration (MIC) of curcumin were evaluated using the CLSI‑M27‑A3, and the MIC of curcumin was compared with that of nystatin. The results were analyzed using the one‑way ANOVA. Results: The MIC of curcumin was 15.6, 32.25, 15.6, 7.8, 32.25, 15.6, 15.6, 15.6, 32.25, and 15.6 μg/mL for the 10 resistant strains and 62.5 μg/mL for the standard strain of C. albicans. Curcumin in the above‑mentioned concentrations significantly inhibited the proliferation of nystatin‑resistant C. albicans strains (P < 0.001). Conclusion: According to this research, it was shown that curcumin with MIC value of 7.8–32.25 μg/mL has inhibitory effects on nystatin‑resistant C. albicans strains. Key Words: Candida albicans, curcumin, nystatin, nystatin‑resistant Candida albicans
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Soha Hajifathali


| Simin Lesan


| Ensieh Lotfali


| Ebrahim Salimi‑Sabour


| Mandana Khatibi


نشانی اینترنتی http://drj.mui.ac.ir/index.php/drj/article/view/2464
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article(s)
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات