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Iranian Journal of Otorhinolaryngology، جلد ۱۹، شماره ۴۸، صفحات ۷۱-۷۷
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عنوان انگلیسی The Comparative study of two treatment protocols in short course control of symptoms of allergic rhinitis patients
چکیده انگلیسی مقاله ]ntroduction: Allergic rhinitis is the most common allergic disorder and its prevalence appears to be increasing. For writing prescription we have to consider some points: efficacy, safety and affordability of drugs and compliance of patient. According to the direct costs of allergic rhinitis, we selected two treatment protocols for comparison. Materials and Methods: 15 to 65 years-old patients suffered from clinical allergic rhinitis at least from one year ago (with annual not seasonal signs and symptoms) referred to Emam Reza hospital arranged in two treatment groups sequentially. After recording the first part of the questionnaire (about their symptoms) treatment started with two protocols. The first was less expensive one included first-generation antihistamine (Chlorpheniramin) and systemic decongestant (Pseudoephedrine) and the second more expensive one consisted of second-generation antihistamine (Loratadine) with inhaled corticosteroid (Beclomethasone). After 45 days the second part of the questionnaire was completed. The patients who changed their jobs during this period were omitted from study. The two protocols were compared with each others by statistics software. Results: Two protocols had similar efficacy on improvement of symptoms such as rhinorrhea, nasal or pharyngeal dryness and itching nasal congestion, PND and sneezing. Conclusion: According to the high price of second protocol and same efficacy of two protocols in some situations such as lack of drug affordability and patients’ preference if there are no contraindications the first protocol could be a good alternative for second one. I
کلیدواژه‌های انگلیسی مقاله Allergic Rhinitis, Systemic decongestant, Antihistamines, Inhaled corticosteroid
نویسندگان مقاله | Mahdi Poorsadegh
Department of Ear, Throat and Nose, Mashhad University of Medical Sciences


| Ehsan khadivi
Department of Ear, Throat and Nose, Mashhad University of Medical Sciences


| Saman Rezaei
Department of Ear, Throat and Nose, Mashhad University of Medical Sciences


| Setareh Sagheb hosseinpoor
General practitioner


| Shiva Gharaei
Internal Department of Mashhad University of Medical Sciences


| Mahasti Babaeyan
Internal Department of Mashhad University of Medical Sciences
نشانی اینترنتی https://ijorl.mums.ac.ir/article_1571.html
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