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Iranian Journal of Microbiology، جلد ۱۵، شماره ۳، صفحات ۴۲۵-۴۳۲
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عنوان انگلیسی Inhibition of bacterial adhesion and anti-biofilm effects of Bacillus cereus and Serratia nematodiphila biosurfactants against Staphylococcus aureus and Pseudomonas aeruginosa
چکیده انگلیسی مقاله Background and Objectives: Biosurfactants are amphiphilic surface-active agents that mainly produced by various microorganisms. In this study, the anti-biofilm and inhibition of bacterial adhesion activities of two bacterial biosurfactants were investigated. Materials and Methods: After extraction and evaluation of Bacillus cereus and Serratia nematodiphila biosurfctants, inhibition of bacterial adhesion and anti-biofilm effects of them on Staphylococcus aureus and Pseudomonas aeruginosa were determined. Results: On average, the synergistic effect of two bacterial biosurfactants, caused about 60% decrease in adhesion and about 80% decrease in biofilm formation of S. aureus and P. aeruginosa. Conclusion: The results of this study showed that combination of B. cereus and S. nematodiphila biosurfactants would increase the potential of attachment inhibition and biofilm eradication with very low toxicity.
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نویسندگان مقاله | Alireza Keyhanian
Infectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran


| Mojgan Mohammadimehr
Infectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran


| Farshad Nojoomi
Infectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran


| Hamed Naghoosi
Infectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran


| Mehdi Shakouri Khomartash
Medical Biotechnology Research Center, Aja University of Medical Sciences, Tehran, Iran


| Mohsen Chamanara
Toxicology Research Center, Aja University of Medical Sciences, Tehran, Iran
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/4117
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