این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Microbiology، جلد ۱۵، شماره ۳، صفحات ۴۶۸-۴۷۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Histopathological characteristics and HPV status in cervical biopsy specimens diagnosed as flat condyloma
چکیده انگلیسی مقاله Background and Objectives: HPV infections cause a wide spectrum of pathological changes in lower anogenital epithelium. The aim of this study was to investigate the HPV DNA status and histological findings in cervical biopsy specimens diagnosed as flat condyloma. Materials and Methods: This study included 20 cervical biopsy specimens diagnosed as flat condyloma. The histopathological criteria and presence of HPV DNA were evaluated. HPV genotyping was determined in HPV-positive specimens using BioEdit software and the results were analyzed in SPSS software. Results: HPV DNA was not found in 30% of specimens and relative frequency of HPV genotypes was: 15% HPV6, 15% HPV11, 5% HPV16, 5% HPV18, 5% HPV53, 5% HPV68, 5% HPV84, 10% HPV45. Relative frequency of histopathological criteria was as below: 100% of specimens had koilocytosis, 100% acanthosis, 15% nuclear immaturity, 100% atypia, 15% mitotic activity, 50% dyskeratosis, 35% parakeratosis and 10% hyperkeratosis. Conclusion: There were significant differences between HPV positivity and two pathologic criteria; multinucleation and hyperkeratosis (P Value: 0.02). Nuclear immaturity was significantly more prevalent in high risk HPV-positive specimens (P Value: 0.03).
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Fatemeh Nategh
Department of Public Medicine, School of Medicine, Tehran Medical Branch, Islamic Azad University, Tehran, Iran


| Mitra Mohit
Department of Obstetrics and Gynecology, Tehran Medical Branch, Islamic Azad University, Tehran, Iran


| Minoo Saatian
Department of Pathology, Tehran Medical Branch, Islamic Azad University, Tehran, Iran


| Zohreh Farahmand
Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran


| Hoorieh Soleimanjahi
Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/4041
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات