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Avicenna Journal of Phytomedicine، جلد ۱۳، شماره ۴، صفحات ۳۳۸-۳۵۳
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عنوان انگلیسی Herbal medicines in the treatment of children and adolescents with attention-deficit/hyperactivity disorder (ADHD): An updated systematic review of clinical trials
چکیده انگلیسی مقاله Objective: This study was performed to provide an updated systematic review of herbal medicines and phytochemicals used for treatment of the pediatric patients with attention-deficit/hyperactivity disorder (ADHD).Materials and Methods: International electronic databases, including Scopus, PubMed, ScienceDirect, and Google Scholar were investigated from 1st January 2000 to late October 2021. Interventional studies published in English language, including randomized controlled trials (RCTs) or open-label clinical studies, which evaluated the effect of herbal medicines and phytochemicals on pediatric ADHD were included in this review.Results: Fifteen studies met the inclusion criteria. Several pieces of evidence support the efficacy of Ginkgo biloba L. and Pycnogenol; mainly inconclusive evidence could be found for Valeriana officinalis L., Melissa officinalis L., and ginseng. The results showed that while Hypericum perforatum L. was ineffective for ADHD, Passiflora incarnata L., Crocus sativus L, and Prunus dulcis (Mill.) D.A.Webb had similar efficacy compared to methylphenidate (MPH).Conclusion: A number of herbal medicines appear to be relatively safe and provide potential efficacy in amelioration of ADHD. However, due to lack of adequate reports of RCTs, no definitely specific recommendations could been made so far.
کلیدواژه‌های انگلیسی مقاله ADHD, Attention-deficit/hyperactivity disorder, Pediatric, Herbal Medicine, Systematic review
نویسندگان مقاله | Haide Golsorkhi
Department of Traditional Medicine, School of Persian Medicine, Iran University of Medical Sciences, Tehran, Iran


| Mostafa Qorbani
Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran. Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran


| Saeideh Sabbaghzadegan
Department of Traditional Medicine, School of Persian Medicine, Iran University of Medical Sciences, Tehran, Iran


| Majid Dadmehr
Department of Traditional Medicine, School of Persian Medicine, Iran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی https://ajp.mums.ac.ir/article_21115.html
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نوع مقاله منتشر شده Review Article
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