این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Organ Transplantation Medicine، جلد ۱۳، شماره ۴، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Renal Transplantation in a Unique Porcine Model: Step-by-Step
چکیده انگلیسی مقاله Objectives: Kidney transplantation is the most common solid organ transplantation. The aim of our research is to describe technical and surgical aspects of a porcine model of heterotopic kidney allotransplantation, using up-to-date techniques, utilized nowadays during human kidney transplantation. Methods: We performed a total of 20 heterotopic kidney transplantations on a porcine animal model. The manipulation time, cold ischemia time and surgery time were measured and analysed over time. Results: Over the course of the experiment manipulation time decreased by 32% from 28min to 19min, cold ischemia time decreased by 33% from 46min to 31min, and surgery time decreased by 28% from 180min to 130min. All animals had successful reperfusion of the grafts. We witnessed urination of all grafts before performing the ureteral anastomosis. Three grafts had an early graft failure due to an early arterial thrombosis; in the first two cases, the grafts had their artery anastomosed onto a thin external iliac artery, the third thrombosis occurred on a graft with complex arterial anatomy with implanted pole artery. Conclusion: Our experimental model demonstrated that a pig laboratory model is a useful and valuable tool for surgical training. It can help to shorten the operation times and lower the complication rates. This specific model can also be extended to serve not only as a simple training tool for surgical techniques. Considering pig to human similarities in physiology, biochemistry, and immunology, it can also be used as a short- or long-term model in kidney transplantation.
کلیدواژه‌های انگلیسی مقاله renal, transplantation, animal, porcine, model, experimental
نویسندگان مقاله | Štěpán Malý
Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic


| Libor Janoušek
Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic


| Zuzana Šimůnková
Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic


| Iveta Mrázová
Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic


| Robert Novotný
Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic


| Jiří Froněk
Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
نشانی اینترنتی http://www.ijotm.com/ojs/index.php/IJOTM/article/view/1017
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات